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A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions.
Kouhnavardi S, Ecevitoglu A, Dragačević V, Sanna F, Arias-Sandoval E, Kalaba P, Kirchhofer M, Lubec J, Niello M, Holy M, Zehl M, Pillwein M, Wackerlig J, Murau R, Mohrmann A, Beard KR, Sitte HH, Urban E, Sagheddu C, Pistis M, Plasenzotti R, Salamone JD, Langer T, Lubec G, Monje FJ. Kouhnavardi S, et al. Biomolecules. 2022 Jun 24;12(7):881. doi: 10.3390/biom12070881. Biomolecules. 2022. PMID: 35883437 Free PMC article.
Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry.
Kalaba P, Pacher K, Neill PJ, Dragacevic V, Zehl M, Wackerlig J, Kirchhofer M, Sartori SB, Gstach H, Kouhnavardi S, Fabisikova A, Pillwein M, Monje-Quiroga F, Ebner K, Prado-Roller A, Singewald N, Urban E, Langer T, Pifl C, Lubec J, Leban JJ, Lubec G. Kalaba P, et al. Among authors: kouhnavardi s. Biomolecules. 2023 Sep 19;13(9):1415. doi: 10.3390/biom13091415. Biomolecules. 2023. PMID: 37759815 Free PMC article.
Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition.
Lubec J, Kalaba P, Hussein AM, Feyissa DD, Kotob MH, Mahmmoud RR, Wieder O, Garon A, Sagheddu C, Ilic M, Dragačević V, Cybulska-Klosowicz A, Zehl M, Wackerlig J, Sartori SB, Ebner K, Kouhnavardi S, Roller A, Gajic N, Pistis M, Singewald N, Leban JJ, Korz V, Malikovic J, Plasenzotti R, Sitte HH, Monje FJ, Langer T, Urban E, Pifl C, Lubec G. Lubec J, et al. Among authors: kouhnavardi s. Mol Psychiatry. 2021 Dec;26(12):7076-7090. doi: 10.1038/s41380-021-01214-x. Mol Psychiatry. 2021. PMID: 34244620
Cognitive performance in aged rats is associated with differences in distinctive neuronal populations in the ventral tegmental area and altered synaptic plasticity in the hippocampus.
Sagheddu C, Stojanovic T, Kouhnavardi S, Savchenko A, Hussein AM, Pistis M, Monje FJ, Plasenzotti R, Aufy M, Studenik CR, Lubec J, Lubec G. Sagheddu C, et al. Among authors: kouhnavardi s. Front Aging Neurosci. 2024 Feb 26;16:1357347. doi: 10.3389/fnagi.2024.1357347. eCollection 2024. Front Aging Neurosci. 2024. PMID: 38469164 Free PMC article.