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Showing results for shi hao tu
Search for Shihao Tu instead (2 results)
Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles.
Hong M, Li Z, Liu H, Zheng S, Zhang F, Zhu J, Shi H, Ye H, Chou Z, Gao L, Diao J, Zhang Y, Zhang D, Chen S, Zhou H, Li J. Hong M, et al. Among authors: shi h. Cell Host Microbe. 2023 May 10;31(5):798-810.e7. doi: 10.1016/j.chom.2023.03.018. Epub 2023 Apr 12. Cell Host Microbe. 2023. PMID: 37054714 Free article.
These findings suggest a causal role of F. nucleatum in aggravating RA and provide promising therapeutic targets for clinically ameliorating RA....
These findings suggest a causal role of F. nucleatum in aggravating RA and provide promising therapeutic targets for clinically ameli …
SLC38A2 and glutamine signalling in cDC1s dictate anti-tumour immunity.
Guo C, You Z, Shi H, Sun Y, Du X, Palacios G, Guy C, Yuan S, Chapman NM, Lim SA, Sun X, Saravia J, Rankin S, Dhungana Y, Chi H. Guo C, et al. Among authors: shi h. Nature. 2023 Aug;620(7972):200-208. doi: 10.1038/s41586-023-06299-8. Epub 2023 Jul 5. Nature. 2023. PMID: 37407815 Free PMC article.
Dendritic cells (DCs), especially type-1 conventional DCs (cDC1s), mediate T cell priming and therapeutic efficacy against tumours(3). DC functions are orchestrated by pattern recognition receptors(3-5), although other signals involved remain incompletely defined. ...Intra …
Dendritic cells (DCs), especially type-1 conventional DCs (cDC1s), mediate T cell priming and therapeutic efficacy against tumours(3) …
Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer.
Zhou P, Shi H, Huang H, Sun X, Yuan S, Chapman NM, Connelly JP, Lim SA, Saravia J, Kc A, Pruett-Miller SM, Chi H. Zhou P, et al. Among authors: shi h. Nature. 2023 Dec;624(7990):154-163. doi: 10.1038/s41586-023-06733-x. Epub 2023 Nov 15. Nature. 2023. PMID: 37968405 Free PMC article.
Accordingly, targeting RBPJ enhanced functional and epigenetic reprogramming of T(ex) cells towards the proliferative state and improved therapeutic effects and ICB efficacy. Collectively, our study reveals that promoting the exit from quiescence of T(pex) cells and enrich …
Accordingly, targeting RBPJ enhanced functional and epigenetic reprogramming of T(ex) cells towards the proliferative state and improved …
Lipid signalling enforces functional specialization of Treg cells in tumours.
Lim SA, Wei J, Nguyen TM, Shi H, Su W, Palacios G, Dhungana Y, Chapman NM, Long L, Saravia J, Vogel P, Chi H. Lim SA, et al. Among authors: shi h. Nature. 2021 Mar;591(7849):306-311. doi: 10.1038/s41586-021-03235-6. Epub 2021 Feb 24. Nature. 2021. PMID: 33627871 Free PMC article.
Regulatory T cells (T(reg) cells) are essential for immune tolerance(1), but also drive immunosuppression in the tumour microenvironment(2). Therapeutic targeting of T(reg) cells in cancer will therefore require the identification of context-specific mechanisms that affect …
Regulatory T cells (T(reg) cells) are essential for immune tolerance(1), but also drive immunosuppression in the tumour microenvironment(2). …
Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia.
Gocho Y, Liu J, Hu J, Yang W, Dharia NV, Zhang J, Shi H, Du G, John A, Lin TN, Hunt J, Huang X, Ju B, Rowland L, Shi L, Maxwell D, Smart B, Crews KR, Yang W, Hagiwara K, Zhang Y, Roberts K, Wang H, Jabbour E, Stock W, Eisfelder B, Paietta E, Newman S, Roti G, Litzow M, Easton J, Zhang J, Peng J, Chi H, Pounds S, Relling MV, Inaba H, Zhu X, Kornblau S, Pui CH, Konopleva M, Teachey D, Mullighan CG, Stegmaier K, Evans WE, Yu J, Yang JJ. Gocho Y, et al. Among authors: shi h. Nat Cancer. 2021 Mar;2(3):284-299. doi: 10.1038/s43018-020-00167-4. Epub 2021 Jan 21. Nat Cancer. 2021. PMID: 34151288 Free PMC article.
Poria cocos polysaccharides rescue pyroptosis-driven gut vascular barrier disruption in order to alleviates non-alcoholic steatohepatitis.
Ye H, Ma S, Qiu Z, Huang S, Deng G, Li Y, Xu S, Yang M, Shi H, Wu C, Li M, Zhang J, Zhang F, Qin M, Huang H, Zeng Z, Wang M, Chen Y, Lin H, Gao Z, Cai M, Song Y, Gong S, Gao L. Ye H, et al. Among authors: shi h. J Ethnopharmacol. 2022 Oct 5;296:115457. doi: 10.1016/j.jep.2022.115457. Epub 2022 Jun 23. J Ethnopharmacol. 2022. PMID: 35753609
Metabolic Control of Treg Cell Stability, Plasticity, and Tissue-Specific Heterogeneity.
Shi H, Chi H. Shi H, et al. Front Immunol. 2019 Dec 11;10:2716. doi: 10.3389/fimmu.2019.02716. eCollection 2019. Front Immunol. 2019. PMID: 31921097 Free PMC article. Review.
Understanding metabolic regulation of Treg cells should provide new insight into immune homeostasis and disease, with important therapeutic implications for autoimmunity, cancer, and other immune-mediated disorders....
Understanding metabolic regulation of Treg cells should provide new insight into immune homeostasis and disease, with important therapeut …
CRISPR-Cas9 knockout screening identifies KIAA1429 as an essential gene in Ewing sarcoma.
Tan K, Lu W, Chen F, Shi H, Ma Y, Chen Z, Wu W, Lv Z, Mo J. Tan K, et al. Among authors: shi h. J Exp Clin Cancer Res. 2023 Sep 28;42(1):250. doi: 10.1186/s13046-023-02828-5. J Exp Clin Cancer Res. 2023. PMID: 37759224 Free PMC article.
CONCLUSION: Our study systematically analyzed ES-dependent epigenetic/transcriptional regulatory genes and identified KIAA1429 as a biomarker of tumor progression in ES, providing a potential therapeutic target for treating ES....
CONCLUSION: Our study systematically analyzed ES-dependent epigenetic/transcriptional regulatory genes and identified KIAA1429 as a biomarke …
75 results