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Page 1
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors.
Nat Chem. 2022 Jan;14(1):15-24. doi: 10.1038/s41557-021-00831-x. Epub 2021 Dec 13.
Nat Chem. 2022.
PMID: 34903857
Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening.
Shishodia S, Nuñez R, Strohmier BP, Bursch KL, Goetz CJ, Olp MD, Jensen DR, Fenske TG, Ordonez-Rubiano SC, Blau ME, Roach MK, Peterson FC, Volkman BF, Dykhuizen EC, Smith BC.
Shishodia S, et al.
J Med Chem. 2022 Oct 27;65(20):13714-13735. doi: 10.1021/acs.jmedchem.2c00864. Epub 2022 Oct 13.
J Med Chem. 2022.
PMID: 36227159
Free PMC article.
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Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors.
Shishodia S, Demetriades M, Zhang D, Tam NY, Maheswaran P, Clunie-O'Connor C, Tumber A, Leung IKH, Ng YM, Leissing TM, El-Sagheer AH, Salah E, Brown T, Aik WS, McDonough MA, Schofield CJ.
Shishodia S, et al.
J Med Chem. 2021 Nov 25;64(22):16609-16625. doi: 10.1021/acs.jmedchem.1c01204. Epub 2021 Nov 11.
J Med Chem. 2021.
PMID: 34762429
Free PMC article.
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Improved Synthesis of Phosphoramidite-Protected N6-Methyladenosine via BOP-Mediated SNAr Reaction.
Shishodia S, Schofield CJ.
Shishodia S, et al.
Molecules. 2020 Dec 31;26(1):147. doi: 10.3390/molecules26010147.
Molecules. 2020.
PMID: 33396208
Free PMC article.
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Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites.
Olp MD, Sprague DJ, Goetz CJ, Kathman SG, Wynia-Smith SL, Shishodia S, Summers SB, Xu Z, Statsyuk AV, Smith BC.
Olp MD, et al. Among authors: shishodia s.
ACS Chem Biol. 2020 Apr 17;15(4):1036-1049. doi: 10.1021/acschembio.0c00058. Epub 2020 Mar 23.
ACS Chem Biol. 2020.
PMID: 32149490
Free PMC article.
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Identification of a pathogenic FTO mutation by next-generation sequencing in a newborn with growth retardation and developmental delay.
Daoud H, Zhang D, McMurray F, Yu A, Luco SM, Vanstone J, Jarinova O, Carson N, Wickens J, Shishodia S, Choi H, McDonough MA, Schofield CJ, Harper ME, Dyment DA, Armour CM.
Daoud H, et al. Among authors: shishodia s.
J Med Genet. 2016 Mar;53(3):200-7. doi: 10.1136/jmedgenet-2015-103399. Epub 2015 Sep 16.
J Med Genet. 2016.
PMID: 26378117
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