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Analysis of Systemic and Serum Risk Factors in Patients with Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy.
Tao T, Xu H, Ma X, Cheng Y, Shi X, Sun Y, Zhao M, Huang L, Li X. Tao T, et al. Among authors: shi x. Ophthalmol Ther. 2023 Apr;12(2):1033-1044. doi: 10.1007/s40123-023-00650-y. Epub 2023 Jan 21. Ophthalmol Ther. 2023. PMID: 36680656 Free PMC article.
METHODS: A retrospective study was performed on 108 patients with nAMD, 131 patients with PCV, and 219 control subjects. Serum levels of total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), apolipoprotein A1 (APOA1), ap …
METHODS: A retrospective study was performed on 108 patients with nAMD, 131 patients with PCV, and 219 control subjects. Serum levels of tot …
Characterization of Fatty Acid Metabolism in Lung Adenocarcinoma.
Wang S, Chen A, Zhu W, Feng D, Wei J, Li Q, Shi X, Lv X, Liu M. Wang S, et al. Among authors: shi x. Front Genet. 2022 Jul 14;13:905508. doi: 10.3389/fgene.2022.905508. eCollection 2022. Front Genet. 2022. PMID: 35910199 Free PMC article.
A nomogram was established based on the FARS and other clinicopathological features, and ROC and calibration plots were used to validate the prediction accuracy. The tumor microenvironment (TME) of patients with high and low FARS was compared. Results: A total of 38 genes …
A nomogram was established based on the FARS and other clinicopathological features, and ROC and calibration plots were used to validate the …
Supraglottic Jet Oxygenation and Ventilation to Minimize Hypoxia in Patients Receiving Flexible Bronchoscopy Under Deep Sedation: A 3-Arm Randomized Controlled Trial.
Wei J, Zhang X, Min K, Zhou H, Shi X, Deng H, Mo W, Wei H, Gu Y, Lv X. Wei J, et al. Among authors: shi x. Anesth Analg. 2024 Feb 1;138(2):456-464. doi: 10.1213/ANE.0000000000006678. Epub 2024 Oct 24. Anesth Analg. 2024. PMID: 37874765 Clinical Trial.
Adult patients scheduled to undergo FB were randomly assigned to 3 groups: NC (oxygen supplementation via NC), low-pressure low-flow (LPLF) (low-pressure oxygen supplementation via WNJ alone), or SJOV (high-pressure oxygen supplementation via WNJ). ...
Adult patients scheduled to undergo FB were randomly assigned to 3 groups: NC (oxygen supplementation via NC), low-pressure low
Discovery of novel 7,7-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidines as ATR inhibitors based on structure-based drug design.
Qi Y, Wang K, Long B, Yue H, Wu Y, Yang D, Tong M, Shi X, Hou Y, Zhao Y. Qi Y, et al. Among authors: shi x. Eur J Med Chem. 2023 Jan 15;246:114945. doi: 10.1016/j.ejmech.2022.114945. Epub 2022 Nov 26. Eur J Med Chem. 2023. PMID: 36462444
Moreover, 48f showed a favorable pharmacokinetic profile with a bioavailability of 30.0% in SD rats, acceptable PPB, high permeability (P(app) A to B = 8.23 cm s(-1) 10(-6)), and low risk of drug-drug interactions. Collectively, compound 48f could be a promising compound f …
Moreover, 48f showed a favorable pharmacokinetic profile with a bioavailability of 30.0% in SD rats, acceptable PPB, high permeability (P(ap …
Quantification of α-hydroxy ceramides in mice serum by LC-MS/MS: Application to sepsis study.
Chao Y, Chen X, Shi X, Li N, Gao S, Yang J, Dong X. Chao Y, et al. Among authors: shi x. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Jun 1;1225:123764. doi: 10.1016/j.jchromb.2023.123764. Epub 2023 May 22. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 37267800
LC-MS/MS method was developed for the accurate quantification of six alpha-hydroxy ceramides of Cer(d18:1/16:0(2OH)), Cer(d18:1/18:0(2OH)), Cer(d18:1/18:1(2OH)), Cer(d18:1/20:0(2OH)), Cer(d18:1/22:0(2OH)) and Cer(d18:1/24:1(2OH)) in mice serum. This assay was validated with lo
LC-MS/MS method was developed for the accurate quantification of six alpha-hydroxy ceramides of Cer(d18:1/16:0(2OH)), Cer(d18:1/18:0(2OH)), …
Determination of arbutin in vitro and in vivo by LC-MS/MS: Pre-clinical evaluation of natural product arbutin for its early medicinal properties.
Wang QL, Zhang PX, Shen R, Xu M, Han L, Shi X, Zhou ZR, Yang JY, Liu JQ. Wang QL, et al. Among authors: shi x. J Ethnopharmacol. 2024 Apr 24;330:118232. doi: 10.1016/j.jep.2024.118232. Online ahead of print. J Ethnopharmacol. 2024. PMID: 38670407 Review.
RESULTS: In vitro studies show that arbutin is stable, albeit with some species differences. It exhibits low plasma protein binding (35.35 11.03% 40.25 2.47%), low lipophilicity, low permeability, short half-life (0.42 0.30 h) and high oral bioavailability (6 …
RESULTS: In vitro studies show that arbutin is stable, albeit with some species differences. It exhibits low plasma protein binding ( …
Assessing the performance of coral reef-like floc towards the removal of low molecular weight organic contaminant.
Zong Y, Jin X, Li Y, Xu L, Shi X, Jin P, Wang XC, Zhang L. Zong Y, et al. Among authors: shi x. Sci Total Environ. 2022 Mar 10;811:152413. doi: 10.1016/j.scitotenv.2021.152413. Epub 2021 Dec 16. Sci Total Environ. 2022. PMID: 34923014
The removal of low molecular weight (MW) organics by coagulation is always a challenge in water treatment. ...Each freshly formed surface bound contaminants and covered the previous surface. As a result, more dissolved low MW organic contaminants were included in th …
The removal of low molecular weight (MW) organics by coagulation is always a challenge in water treatment. ...Each freshly formed sur …
Characteristics of dissolved ozone flotation for the enhanced treatment of bio-treated drilling wastewater from a gas field.
Jin X, Zhang L, Liu M, Hu S, Yao Z, Liang J, Wang R, Xu L, Shi X, Bai X, Jin P, Wang XC. Jin X, et al. Among authors: shi x. Chemosphere. 2022 Jul;298:134290. doi: 10.1016/j.chemosphere.2022.134290. Epub 2022 Mar 9. Chemosphere. 2022. PMID: 35278446
Working fluid preparation using treated drilling wastewater is of great potential for drilling wastewater reuse, especially in water-deficient and ecologically fragile areas, which require low levels of organic matter and suspended solids (SS). This study established the d …
Working fluid preparation using treated drilling wastewater is of great potential for drilling wastewater reuse, especially in water-deficie …
Diversified metabolism makes novel Thauera strain highly competitive in low carbon wastewater treatment.
Ren T, Chi Y, Wang Y, Shi X, Jin X, Jin P. Ren T, et al. Among authors: shi x. Water Res. 2021 Nov 1;206:117742. doi: 10.1016/j.watres.2021.117742. Epub 2021 Oct 7. Water Res. 2021. PMID: 34653797
Thauera, as one of the core members of wastewater biological treatment systems, plays an important role in the process of nitrogen and phosphorus removal from low-carbon source sewage. However, there is a lack of systematic understanding of Thauera's metabolic pathway and …
Thauera, as one of the core members of wastewater biological treatment systems, plays an important role in the process of nitrogen and phosp …
Unraveling the over-oxidation inhibition mechanism during the hybrid ozonation-coagulation process: Immediate entrapment and complexation between intermediate organic matter and coagulants.
Jin X, Liu M, Zong Y, Hu S, Li Y, Xu L, Bai X, Shi X, Jin P, Song J, Wang XC. Jin X, et al. Among authors: shi x. Water Res. 2023 Apr 1;232:119692. doi: 10.1016/j.watres.2023.119692. Epub 2023 Feb 3. Water Res. 2023. PMID: 36758355
Pre-ozonation coagulation process had a very low and narrow range of ozone dosages for enhancing the dissolved organic matter (DOC) removal efficiency, in which over-oxidation may occur if the ozone dosage was not strictly controlled. ...
Pre-ozonation coagulation process had a very low and narrow range of ozone dosages for enhancing the dissolved organic matter (DOC) r …
25 results