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Year | Number of Results |
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2017 | 2 |
2022 | 3 |
2024 | 1 |
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Page 1
A Selective Review and Virtual Screening Analysis of Natural Product Inhibitors of the NLRP3 Inflammasome.
Molecules. 2022 Sep 21;27(19):6213. doi: 10.3390/molecules27196213.
Molecules. 2022.
PMID: 36234744
Free PMC article.
Review.
Brazilin is a natural product inhibitor of the NLRP3 inflammasome.
McMahon E, El-Sayed S, Green J, Hoyle C, FitzPatrick L, Jones EV, Corrie E, Kelly RL, Challinor M, Freeman S, Bryce RA, Lawrence CB, Brough D, Kasher PR.
McMahon E, et al. Among authors: el sayed s.
iScience. 2024 Jan 19;27(2):108968. doi: 10.1016/j.isci.2024.108968. eCollection 2024 Feb 16.
iScience. 2024.
PMID: 38327788
Free PMC article.
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Probing the effect of NEK7 and cofactor interactions on dynamics of NLRP3 monomer using molecular simulation.
El-Sayed S, Freeman S, Bryce RA.
El-Sayed S, et al.
Protein Sci. 2022 Oct;31(10):e4420. doi: 10.1002/pro.4420.
Protein Sci. 2022.
PMID: 36173167
Free PMC article.
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SAR of Novel 3-Arylisoquinolinones: meta-Substitution on the Aryl Ring Dramatically Enhances Antiproliferative Activity through Binding to Microtubules.
Elhemely MA, Belgath AA, El-Sayed S, Burusco KK, Kadirvel M, Tirella A, Finegan K, Bryce RA, Stratford IJ, Freeman S.
Elhemely MA, et al. Among authors: el sayed s.
J Med Chem. 2022 Mar 24;65(6):4783-4797. doi: 10.1021/acs.jmedchem.1c01936. Epub 2022 Mar 15.
J Med Chem. 2022.
PMID: 35290041
Free PMC article.
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Synthesis and anticancer activity of novel quinazolinone-based rhodanines.
El-Sayed S, Metwally K, El-Shanawani AA, Abdel-Aziz LM, Pratsinis H, Kletsas D.
El-Sayed S, et al.
Chem Cent J. 2017 Oct 13;11(1):102. doi: 10.1186/s13065-017-0333-x.
Chem Cent J. 2017.
PMID: 29086906
Free PMC article.
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Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study.
El-Sayed S, Metwally K, El-Shanawani AA, Abdel-Aziz LM, El-Rashedy AA, Soliman MES, Quattrini L, Coviello V, la Motta C.
El-Sayed S, et al.
Bioorg Med Chem Lett. 2017 Oct 15;27(20):4760-4764. doi: 10.1016/j.bmcl.2017.08.050. Epub 2017 Aug 24.
Bioorg Med Chem Lett. 2017.
PMID: 28935265
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