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Showing results for shaoxing brain xu
Search for Shaoxiong Brian Xu instead (3 results)
SARM1 deletion in parvalbumin neurons is associated with autism-like behaviors in mice.
Xiang L, Wu Q, Sun H, Miao X, Lv Z, Liu H, Chen L, Gu Y, Chen J, Zhou S, Jiang H, Du S, Zhou Y, Dong H, Fan Y, Miao S, Lu Q, Chang L, Wang H, Lu Y, Xu X, Wang W, Huang Z. Xiang L, et al. Cell Death Dis. 2022 Jul 22;13(7):638. doi: 10.1038/s41419-022-05083-2. Cell Death Dis. 2022. PMID: 35869039 Free PMC article.
Sterile alpha and TIR motif-containing 1 protein (SARM1) is known as an autism-associated protein and is enriched in brain tissue. Moreover, SARM1 knockdown mice exhibit autism-like behaviors. ...
Sterile alpha and TIR motif-containing 1 protein (SARM1) is known as an autism-associated protein and is enriched in brain tissue. Mo …
MicroRNA-195 liposomes for therapy of Alzheimer's disease.
Su D, Chen Z, An X, Yang J, Yang J, Wang X, Qu Y, Gong C, Chai Y, Liu X, Cheng W, Wang D, Wu Y, Ma J, Zhao X, Wang Q, Xu Y, Peng H, Ai J. Su D, et al. J Control Release. 2024 Jan;365:583-601. doi: 10.1016/j.jconrel.2023.12.003. Epub 2023 Dec 6. J Control Release. 2024. PMID: 38048963
Nonetheless, as RNA-based drugs, their stability in the circulation and capacity of traversing the blood-brain barrier (BBB) is largely compromised, thereby limiting their potential clinical applications. ...
Nonetheless, as RNA-based drugs, their stability in the circulation and capacity of traversing the blood-brain barrier (BBB) is large …
Familial and genetic association with neurodevelopmental disorders caused by a heterozygous variant in the SRRM2 gene.
Zhang T, Xu L, Zhu H, Ying Y, Ding J, Ding H, Shi X, He Y, Jin X, Xia G. Zhang T, et al. Front Endocrinol (Lausanne). 2023 Aug 9;14:1240168. doi: 10.3389/fendo.2023.1240168. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37621647 Free PMC article.
BACKGROUND: Neurodevelopmental disorders (NDDs) are a class of disorders affecting brain development and function, characterized by an inability to reach cognitive, emotional, and motor developmental milestones. ...
BACKGROUND: Neurodevelopmental disorders (NDDs) are a class of disorders affecting brain development and function, characterized by a …
GABAergic Inhibitory Interneuron Deficits in Alzheimer's Disease: Implications for Treatment.
Xu Y, Zhao M, Han Y, Zhang H. Xu Y, et al. Front Neurosci. 2020 Jun 30;14:660. doi: 10.3389/fnins.2020.00660. eCollection 2020. Front Neurosci. 2020. PMID: 32714136 Free PMC article. Review.
Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by severe cognitive deficits and pathologically by amyloid plaques, neuronal loss, and neurofibrillary tangles. Abnormal amyloid beta-protein (Abeta) deposition in the brain is often thought …
Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by severe cognitive deficits and pathologically by amyloid …
The application of multifunctional nanomaterials in Alzheimer's disease: A potential theranostics strategy.
Xu Y, Zhao M, Zhou D, Zheng T, Zhang H. Xu Y, et al. Biomed Pharmacother. 2021 May;137:111360. doi: 10.1016/j.biopha.2021.111360. Epub 2021 Feb 11. Biomed Pharmacother. 2021. PMID: 33582451 Free article. Review.
By virtue of their small size, nanomaterials can cross the blood-brain barrier and, when modified to target specific cells or regions, can achieve high bioavailability at the intended site of action. ...
By virtue of their small size, nanomaterials can cross the blood-brain barrier and, when modified to target specific cells or regions …
Mesenchymal stem cell-derived extracellular vesicles affect disease outcomes via transfer of microRNAs.
Qiu G, Zheng G, Ge M, Wang J, Huang R, Shu Q, Xu J. Qiu G, et al. Stem Cell Res Ther. 2018 Nov 21;9(1):320. doi: 10.1186/s13287-018-1069-9. Stem Cell Res Ther. 2018. PMID: 30463593 Free PMC article. Review.
Next, we provide the existing evidence that MSC-EVs affect the outcomes of renal, liver, heart, and brain diseases by transferring their miRNA contents. In conclusion, EV-mediated miRNA transfer plays an important role in disease-modulating capacity of MSCs....
Next, we provide the existing evidence that MSC-EVs affect the outcomes of renal, liver, heart, and brain diseases by transferring th …
Vagus Nerve Stimulation Relives Irritable Bowel Syndrome and the Associated Depression via α7nAChR-mediated Anti-inflammatory Pathway.
Yan Q, Chen J, Ren X, Song Y, Xu J, Xuan S, Jiang X, Kuang Z, Tang Z. Yan Q, et al. Neuroscience. 2023 Oct 15;530:26-37. doi: 10.1016/j.neuroscience.2023.08.026. Epub 2023 Aug 23. Neuroscience. 2023. PMID: 37625687
Subdiaphragmatic vagotomy (SDV) and vagus nerve stimulation (VNS) were performed to intervene the excitability of vagus nerve. Permeability of blood brain barrier (BBB) was measured and agonist and antagonist of alpha7 nicotinic acetylcholine receptor (alpha7nAChR) were us …
Subdiaphragmatic vagotomy (SDV) and vagus nerve stimulation (VNS) were performed to intervene the excitability of vagus nerve. Permeability …
Mesenchymal Stromal Cells Affect Disease Outcomes via Macrophage Polarization.
Zheng G, Ge M, Qiu G, Shu Q, Xu J. Zheng G, et al. Stem Cells Int. 2015;2015:989473. doi: 10.1155/2015/989473. Epub 2015 Jul 15. Stem Cells Int. 2015. PMID: 26257791 Free PMC article. Review.
In this review, we discuss the central role of MSCs in macrophage polarization and outcomes of diseases such as wound healing, brain/spinal cord injuries, and diseases of heart, lung, and kidney in animal models....
In this review, we discuss the central role of MSCs in macrophage polarization and outcomes of diseases such as wound healing, brain/ …
Altered Functional Brain Network Structure between Patients with High and Low Generalized Anxiety Disorder.
Qi X, Fang J, Sun Y, Xu W, Li G. Qi X, et al. Diagnostics (Basel). 2023 Mar 29;13(7):1292. doi: 10.3390/diagnostics13071292. Diagnostics (Basel). 2023. PMID: 37046509 Free PMC article.
Functional connectivity between all pairs of brain regions was determined by the Phase Lag Index (PLI) to construct a functional brain network. ...Our findings may play a role in the development and understanding of LGAD and HGAD to determine whether interventions t …
Functional connectivity between all pairs of brain regions was determined by the Phase Lag Index (PLI) to construct a functional b …
Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification.
Cen Z, Chen Y, Chen S, Wang H, Yang D, Zhang H, Wu H, Wang L, Tang S, Ye J, Shen J, Wang H, Fu F, Chen X, Xie F, Liu P, Xu X, Cao J, Cai P, Pan Q, Li J, Yang W, Shan PF, Li Y, Liu JY, Zhang B, Luo W. Cen Z, et al. Brain. 2020 Feb 1;143(2):491-502. doi: 10.1093/brain/awz392. Brain. 2020. PMID: 31851307
Primary familial brain calcification is a monogenic disease characterized by bilateral calcifications in the basal ganglia and other brain regions, and commonly presents motor, psychiatric, and cognitive symptoms. ...This is similar to the mechanisms of other causat …
Primary familial brain calcification is a monogenic disease characterized by bilateral calcifications in the basal ganglia and other …
67 results