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SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP Jr, Bjorkman PJ. Barnes CO, et al. Among authors: esswein sr. Nature. 2020 Dec;588(7839):682-687. doi: 10.1038/s41586-020-2852-1. Epub 2020 Oct 12. Nature. 2020. PMID: 33045718 Free PMC article.
A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques.
Van Rompay KKA, Coffey LL, Kapoor T, Gazumyan A, Keesler RI, Jurado A, Peace A, Agudelo M, Watanabe J, Usachenko J, Singapuri A, Immareddy R, Ardeshir A, Stuart JB, Bournazos S, Ravetch JV, Balderes PJ, Lorenz IC, Esswein SR, Keeffe JR, Bjorkman PJ, Wang Q, Rice CM, MacDonald MR, Nussenzweig MC, Robbiani DF. Van Rompay KKA, et al. Among authors: esswein sr. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7981-7989. doi: 10.1073/pnas.2000414117. Epub 2020 Mar 24. Proc Natl Acad Sci U S A. 2020. PMID: 32209664 Free PMC article.
Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies.
Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP Jr, Bjorkman PJ. Barnes CO, et al. Among authors: esswein sr. bioRxiv [Preprint]. 2020 Aug 30:2020.08.30.273920. doi: 10.1101/2020.08.30.273920. bioRxiv. 2020. PMID: 32869026 Free PMC article. Updated. Preprint.
Formation of amyloid fibers by monomeric light chain variable domains.
Brumshtein B, Esswein SR, Landau M, Ryan CM, Whitelegge JP, Phillips ML, Cascio D, Sawaya MR, Eisenberg DS. Brumshtein B, et al. Among authors: esswein sr. J Biol Chem. 2014 Oct 3;289(40):27513-25. doi: 10.1074/jbc.M114.585638. Epub 2014 Aug 19. J Biol Chem. 2014. PMID: 25138218 Free PMC article.