The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial.
Yaskolka Meir A, Keller M, Hoffmann A, Rinott E, Tsaban G, Kaplan A, Zelicha H, Hagemann T, Ceglarek U, Isermann B, Shelef I, Blüher M, Stumvoll M, Li J, Haange SB, Engelmann B, Rolle-Kampczyk U, von Bergen M, Hu FB, Stampfer MJ, Kovacs P, Liang L, Shai I.
Yaskolka Meir A, et al.
BMC Med. 2023 Sep 25;21(1):364. doi: 10.1186/s12916-023-03067-3.
BMC Med. 2023.
PMID: 37743489
Free PMC article.
Clinical Trial.
While all interventions did not differ in terms of changes between mAge clocks, greater Green-Med diet adherence was associated with a lower 18-month relative change (i.e., greater mAge attenuation) in Li and Hannum mAge (beta = - 0.41, p = 0.004 and beta = - 0.38, p = 0.0 …
While all interventions did not differ in terms of changes between mAge clocks, greater Green-Med diet adherence was associated with a lower …