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Page 1
Showing results for severe pasca
Search for Sever Pasca instead (1 results)
Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome.
Birey F, Li MY, Gordon A, Thete MV, Valencia AM, Revah O, Paşca AM, Geschwind DH, Paşca SP. Birey F, et al. Cell Stem Cell. 2022 Feb 3;29(2):248-264.e7. doi: 10.1016/j.stem.2021.11.011. Epub 2022 Jan 5. Cell Stem Cell. 2022. PMID: 34990580 Free article.
Using forebrain assembloids derived by integration of cortical and ventral forebrain organoids, we have previously discovered a cortical interneuron migration defect in Timothy syndrome (TS), a severe neurodevelopmental disease caused by a mutation in the L-type calcium ch …
Using forebrain assembloids derived by integration of cortical and ventral forebrain organoids, we have previously discovered a cortical int …
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism.
Hokusai-VTE Investigators; Büller HR, Décousus H, Grosso MA, Mercuri M, Middeldorp S, Prins MH, Raskob GE, Schellong SM, Schwocho L, Segers A, Shi M, Verhamme P, Wells P. Hokusai-VTE Investigators, et al. N Engl J Med. 2013 Oct 10;369(15):1406-15. doi: 10.1056/NEJMoa1306638. Epub 2013 Aug 31. N Engl J Med. 2013. PMID: 23991658 Free article. Clinical Trial.
CONCLUSIONS: Edoxaban administered once daily after initial treatment with heparin was noninferior to high-quality standard therapy and caused significantly less bleeding in a broad spectrum of patients with venous thromboembolism, including those with severe pulmonary emb …
CONCLUSIONS: Edoxaban administered once daily after initial treatment with heparin was noninferior to high-quality standard therapy and caus …
Updates on Novel Non-Replacement Drugs for Hemophilia.
Gualtierotti R, Pasca S, Ciavarella A, Arcudi S, Giachi A, Garagiola I, Suffritti C, Siboni SM, Peyvandi F. Gualtierotti R, et al. Pharmaceuticals (Basel). 2022 Sep 23;15(10):1183. doi: 10.3390/ph15101183. Pharmaceuticals (Basel). 2022. PMID: 36297295 Free PMC article. Review.
Apart from the bispecific monoclonal antibody emicizumab, already approved for patients with severe hemophilia A with and without inhibitors, novel non-replacement drugs designed to reduce the treatment burden of patients with hemophilia A or B with or without inhibitors a …
Apart from the bispecific monoclonal antibody emicizumab, already approved for patients with severe hemophilia A with and without inh …
Antisense oligonucleotide therapeutic approach for Timothy syndrome.
Chen X, Birey F, Li MY, Revah O, Levy R, Thete MV, Reis N, Kaganovsky K, Onesto M, Sakai N, Hudacova Z, Hao J, Meng X, Nishino S, Huguenard J, Pașca SP. Chen X, et al. Nature. 2024 Apr;628(8009):818-825. doi: 10.1038/s41586-024-07310-6. Epub 2024 Apr 24. Nature. 2024. PMID: 38658687 Free PMC article.
Timothy syndrome (TS) is a severe, multisystem disorder characterized by autism, epilepsy, long-QT syndrome and other neuropsychiatric conditions(1). ...
Timothy syndrome (TS) is a severe, multisystem disorder characterized by autism, epilepsy, long-QT syndrome and other neuropsychiatri …
Therapeutic dilemmas in addressing SARS-CoV-2 infection: Favipiravir versus Remdesivir.
Negru PA, Radu AF, Vesa CM, Behl T, Abdel-Daim MM, Nechifor AC, Endres L, Stoicescu M, Pasca B, Tit DM, Bungau SG. Negru PA, et al. Biomed Pharmacother. 2022 Mar;147:112700. doi: 10.1016/j.biopha.2022.112700. Epub 2022 Feb 4. Biomed Pharmacother. 2022. PMID: 35131656 Free PMC article. Review.
Clinically proven efficacy and safety profiles have made favipiravir (FVP) and remdesivir (RDV) promising therapeutic options for use against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. ...
Clinically proven efficacy and safety profiles have made favipiravir (FVP) and remdesivir (RDV) promising therapeutic options for use agains …
Ketosis and migraine: a systematic review of the literature and meta-analysis.
Neri LCL, Ferraris C, Catalano G, Guglielmetti M, Pasca L, Pezzotti E, Carpani A, Tagliabue A. Neri LCL, et al. Front Nutr. 2023 Jun 12;10:1204700. doi: 10.3389/fnut.2023.1204700. eCollection 2023. Front Nutr. 2023. PMID: 37377485 Free PMC article.
One promising approach is ketogenic therapy, which replaces the brain's glucose fuel source with ketone bodies, potentially reducing the frequency or severity of headaches. AIM: This study aims to conduct a systematic review of the scientific literature on the impact of ke …
One promising approach is ketogenic therapy, which replaces the brain's glucose fuel source with ketone bodies, potentially reducing the fre …
Analysis of serum levels L-arginine and 25-hydroxyvitamin D as a predictor of survival of severe preeclampsia mothers.
Wahyuningsih D, Usman AN, Prihantono. Wahyuningsih D, et al. Gac Sanit. 2021;35 Suppl 2:S224-S226. doi: 10.1016/j.gaceta.2021.10.026. Gac Sanit. 2021. PMID: 34929817 Free article.
The samples of this study were mothers who gave birth with a diagnosis of normal pregnant women, severe preeclampsia, and severe preeclampsia with complications. RESULTS: Serum l-arginine level did not affect the survival of severe preeclamptic mothers. ...In …
The samples of this study were mothers who gave birth with a diagnosis of normal pregnant women, severe preeclampsia, and severe …
Intracranial haemorrhage in children and adults with haemophilia A and B: a literature review of the last 20 years.
Zanon E, Pasca S. Zanon E, et al. Blood Transfus. 2019 Sep;17(5):378-384. doi: 10.2450/2019.0253-18. Epub 2018 Feb 4. Blood Transfus. 2019. PMID: 30747705 Free PMC article. Review.
Greater attention to risk factors and early symptoms, together with an appropriate early prophylaxis, may reduce the risk of severe intracranial haemorrhagic events....
Greater attention to risk factors and early symptoms, together with an appropriate early prophylaxis, may reduce the risk of severe i …
ABO Blood Group and Inhibitor Risk in Severe Hemophilia A Patients: A Study from the Italian Association of Hemophilia Centers.
Franchini M, Coppola A, Santoro C, De Cristofaro R, Barillari G, Giordano P, Gresele P, Lassandro G, Napolitano M, Lucchini G, Luciani M, Ferretti A, Baldacci E, Riccardi F, Santoro RC, Pasca S, Zanon E, Tagliaferri A. Franchini M, et al. Semin Thromb Hemost. 2021 Feb;47(1):84-89. doi: 10.1055/s-0040-1718870. Epub 2021 Feb 1. Semin Thromb Hemost. 2021. PMID: 33525041
Considering the profound influence exerted by the ABO blood group system on hemostasis, mainly through the von Willebrand factor and factor VIII (FVIII) complex, we have conducted a study evaluating the possible role of blood type on the risk of inhibitor development in hemophili …
Considering the profound influence exerted by the ABO blood group system on hemostasis, mainly through the von Willebrand factor and factor …
69 results