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Year | Number of Results |
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2014 | 1 |
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Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index.
Nat Biotechnol. 2019 Jun;37(6):640-650. doi: 10.1038/s41587-019-0106-2. Epub 2019 Apr 29.
Nat Biotechnol. 2019.
PMID: 31036929
Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages.
Wan WB, Migawa MT, Vasquez G, Murray HM, Nichols JG, Gaus H, Berdeja A, Lee S, Hart CE, Lima WF, Swayze EE, Seth PP.
Wan WB, et al. Among authors: seth pp.
Nucleic Acids Res. 2014 Dec 16;42(22):13456-68. doi: 10.1093/nar/gku1115. Epub 2014 Nov 14.
Nucleic Acids Res. 2014.
PMID: 25398895
Free PMC article.
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Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis.
Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ, Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA, Dubois B, Hauser SL, Garcia-Blanco MA, Pericak-Vance MA, Haines JL; Multiple Sclerosis Genetics Group.
Gregory SG, et al. Among authors: seth p.
Nat Genet. 2007 Sep;39(9):1083-91. doi: 10.1038/ng2103. Epub 2007 Jul 29.
Nat Genet. 2007.
PMID: 17660817
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Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts.
Burel SA, Hart CE, Cauntay P, Hsiao J, Machemer T, Katz M, Watt A, Bui HH, Younis H, Sabripour M, Freier SM, Hung G, Dan A, Prakash TP, Seth PP, Swayze EE, Bennett CF, Crooke ST, Henry SP.
Burel SA, et al. Among authors: seth pp.
Nucleic Acids Res. 2016 Mar 18;44(5):2093-109. doi: 10.1093/nar/gkv1210. Epub 2015 Nov 8.
Nucleic Acids Res. 2016.
PMID: 26553810
Free PMC article.
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