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Page 1
Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment.
Alapafuja SO, Malamas MS, Shukla V, Zvonok A, Miller S, Daily L, Rajarshi G, Miyabe CY, Chandrashekhar H, Wood J, Tyukhtenko S, Straiker A, Makriyannis A. Alapafuja SO, et al. Among authors: tyukhtenko s. Bioorg Med Chem. 2019 Jan 1;27(1):55-64. doi: 10.1016/j.bmc.2018.11.003. Epub 2018 Nov 3. Bioorg Med Chem. 2019. PMID: 30446439 Free PMC article.
Identification by nuclear magnetic resonance spectroscopy of an active-site hydrogen-bond network in human monoacylglycerol lipase (hMGL): implications for hMGL dynamics, pharmacological inhibition, and catalytic mechanism.
Karageorgos I, Tyukhtenko S, Zvonok N, Janero DR, Sallum C, Makriyannis A. Karageorgos I, et al. Among authors: tyukhtenko s. Mol Biosyst. 2010 Aug;6(8):1381-8. doi: 10.1039/c004515b. Epub 2010 May 12. Mol Biosyst. 2010. PMID: 20464001 Free PMC article.
16 results