Novel Photonic Bio-Chip Sensor Based on Strained Graphene Sheets for Blood Cell Sorting

Molecules. 2021 Sep 14;26(18):5585. doi: 10.3390/molecules26185585.

Abstract

A photonic biochip with a tunable response in the visible range is suggested for blood cell sorting applications. Multi-layers of ZnS and Ge slabs (as the main building blocks), hosting a cell in which bio-sample could be injected, are considered as the core of the sensor. In order to increase the sensitivity of the chip, the bio-cell is capsulated inside air slabs, and its walls are coated with graphene sheets. Paying special attention to white and red blood components, the optimum values for structural parameters are extracted first. Tunability of the sensor detectivity is then explored by finding the role of the probe light incident angle, as well as its polarization. The strain of the graphene layer and angle in which it is applied are also suggested to further improve the performance tunability. Results reflect that the biochip can effectively identify selected components through their induced different optical features, besides of the different figure of merit and sensitivity amounts that are recorded for them by the sensor.

Keywords: biosensor; graphene; label-free; photonic crystal; strain; tunable.

MeSH terms

  • Biosensing Techniques
  • Blood Cells*
  • Cell Separation*
  • Equipment Design
  • Graphite
  • Optics and Photonics

Substances

  • Graphite