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Page 1
Early cell death induced by Clostridium difficile TcdB: Uptake and Rac1-glucosylation kinetics are decisive for cell fate.
Cell Microbiol. 2018 Oct;20(10):e12865. doi: 10.1111/cmi.12865. Epub 2018 Jun 28.
Cell Microbiol. 2018.
PMID: 29904993
Development of Neutralizing and Non-neutralizing Antibodies Targeting Known and Novel Epitopes of TcdB of Clostridioides difficile.
Fühner V, Heine PA, Helmsing S, Goy S, Heidepriem J, Loeffler FF, Dübel S, Gerhard R, Hust M.
Fühner V, et al. Among authors: goy s.
Front Microbiol. 2018 Dec 6;9:2908. doi: 10.3389/fmicb.2018.02908. eCollection 2018.
Front Microbiol. 2018.
PMID: 30574127
Free PMC article.
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Cellular uptake of Clostridium difficile TcdA and truncated TcdA lacking the receptor binding domain.
Gerhard R, Frenzel E, Goy S, Olling A.
Gerhard R, et al. Among authors: goy s.
J Med Microbiol. 2013 Sep;62(Pt 9):1414-1422. doi: 10.1099/jmm.0.057828-0. Epub 2013 Apr 4.
J Med Microbiol. 2013.
PMID: 23558138
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Human neutrophils are activated by a peptide fragment of Clostridium difficile toxin B presumably via formyl peptide receptor.
Goy SD, Olling A, Neumann D, Pich A, Gerhard R.
Goy SD, et al.
Cell Microbiol. 2015 Jun;17(6):893-909. doi: 10.1111/cmi.12410. Epub 2015 Jan 26.
Cell Microbiol. 2015.
PMID: 25529763
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The repetitive oligopeptide sequences modulate cytopathic potency but are not crucial for cellular uptake of Clostridium difficile toxin A.
Olling A, Goy S, Hoffmann F, Tatge H, Just I, Gerhard R.
Olling A, et al. Among authors: goy s.
PLoS One. 2011 Mar 18;6(3):e17623. doi: 10.1371/journal.pone.0017623.
PLoS One. 2011.
PMID: 21445253
Free PMC article.
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Pyknotic cell death induced by Clostridium difficile TcdB: chromatin condensation and nuclear blister are induced independently of the glucosyltransferase activity.
Wohlan K, Goy S, Olling A, Srivaratharajan S, Tatge H, Genth H, Gerhard R.
Wohlan K, et al. Among authors: goy s.
Cell Microbiol. 2014 Nov;16(11):1678-92. doi: 10.1111/cmi.12317. Epub 2014 Aug 4.
Cell Microbiol. 2014.
PMID: 24898616
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The combined repetitive oligopeptides of clostridium difficile toxin A counteract premature cleavage of the glucosyl-transferase domain by stabilizing protein conformation.
Olling A, Hüls C, Goy S, Müller M, Krooss S, Rudolf I, Tatge H, Gerhard R.
Olling A, et al. Among authors: goy s.
Toxins (Basel). 2014 Jul 22;6(7):2162-76. doi: 10.3390/toxins6072162.
Toxins (Basel). 2014.
PMID: 25054784
Free PMC article.
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