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2021 | 3 |
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Page 1
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities.
Cancer Cell. 2021 Mar 8;39(3):346-360.e7. doi: 10.1016/j.ccell.2020.12.014. Epub 2021 Jan 21.
Cancer Cell. 2021.
PMID: 33482121
Free PMC article.
ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer.
Olsen RR, Ireland AS, Kastner DW, Groves SM, Spainhower KB, Pozo K, Kelenis DP, Whitney CP, Guthrie MR, Wait SJ, Soltero D, Witt BL, Quaranta V, Johnson JE, Oliver TG.
Olsen RR, et al. Among authors: groves sm.
Genes Dev. 2021 Jun;35(11-12):847-869. doi: 10.1101/gad.348295.121. Epub 2021 May 20.
Genes Dev. 2021.
PMID: 34016693
Free PMC article.
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Quantifying cancer cell plasticity with gene regulatory networks and single-cell dynamics.
Groves SM, Quaranta V.
Groves SM, et al.
Front Netw Physiol. 2023 Sep 4;3:1225736. doi: 10.3389/fnetp.2023.1225736. eCollection 2023.
Front Netw Physiol. 2023.
PMID: 37731743
Free PMC article.
Review.
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Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer.
Groves SM, Ildefonso GV, McAtee CO, Ozawa PMM, Ireland AS, Stauffer PE, Wasdin PT, Huang X, Qiao Y, Lim JS, Bader J, Liu Q, Simmons AJ, Lau KS, Iams WT, Hardin DP, Saff EB, Holmes WR, Tyson DR, Lovly CM, Rathmell JC, Marth G, Sage J, Oliver TG, Weaver AM, Quaranta V.
Groves SM, et al.
Cell Syst. 2022 Sep 21;13(9):690-710.e17. doi: 10.1016/j.cels.2022.07.006. Epub 2022 Aug 17.
Cell Syst. 2022.
PMID: 35981544
Free PMC article.
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Beyond Programmed Death-Ligand 1: B7-H6 Emerges as a Potential Immunotherapy Target in SCLC.
Thomas PL, Groves SM, Zhang YK, Li J, Gonzalez-Ericsson P, Sivagnanam S, Betts CB, Chen HC, Liu Q, Lowe C, Chen H, Boyd KL, Kopparapu PR, Yan Y, Coussens LM, Quaranta V, Tyson DR, Iams W, Lovly CM.
Thomas PL, et al. Among authors: groves sm.
J Thorac Oncol. 2021 Jul;16(7):1211-1223. doi: 10.1016/j.jtho.2021.03.011. Epub 2021 Apr 8.
J Thorac Oncol. 2021.
PMID: 33839362
Free PMC article.
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Involvement of Epithelial-Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity.
Groves SM, Panchy N, Tyson DR, Harris LA, Quaranta V, Hong T.
Groves SM, et al.
Cancers (Basel). 2023 Feb 25;15(5):1477. doi: 10.3390/cancers15051477.
Cancers (Basel). 2023.
PMID: 36900269
Free PMC article.
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Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers.
Wooten DJ, Groves SM, Tyson DR, Liu Q, Lim JS, Albert R, Lopez CF, Sage J, Quaranta V.
Wooten DJ, et al. Among authors: groves sm.
PLoS Comput Biol. 2019 Oct 31;15(10):e1007343. doi: 10.1371/journal.pcbi.1007343. eCollection 2019 Oct.
PLoS Comput Biol. 2019.
PMID: 31671086
Free PMC article.
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