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Novel potent (dihydro)benzofuranyl piperazines as human histamine receptor ligands - Functional characterization and modeling studies on H3 and H4 receptors.
Corrêa MF, Balico-Silva AL, Kiss DJ, Fernandes GAB, Maraschin JC, Parreiras-E-Silva LT, Varela MT, Simões SC, Bouvier M, Keserű GM, Costa-Neto CM, Fernandes JPS. Corrêa MF, et al. Among authors: simoes sc. Bioorg Med Chem. 2021 Jan 15;30:115924. doi: 10.1016/j.bmc.2020.115924. Epub 2020 Dec 8. Bioorg Med Chem. 2021. PMID: 33333448
Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy.
Teixeira LB, Parreiras-E-Silva LT, Bruder-Nascimento T, Duarte DA, Simões SC, Costa RM, Rodríguez DY, Ferreira PAB, Silva CAA, Abrao EP, Oliveira EB, Bouvier M, Tostes RC, Costa-Neto CM. Teixeira LB, et al. Among authors: simoes sc. Sci Rep. 2017 Sep 19;7(1):11903. doi: 10.1038/s41598-017-12074-3. Sci Rep. 2017. PMID: 28928410 Free PMC article.
Pharmacological Characterization of 5-Substituted 1-[(2,3-dihydro-1-benzofuran-2-yl)methyl]piperazines: Novel Antagonists for the Histamine H3 and H4 Receptors with Anti-inflammatory Potential.
Corrêa MF, Barbosa ÁJR, Teixeira LB, Duarte DA, Simões SC, Parreiras-E-Silva LT, Balbino AM, Landgraf RG, Bouvier M, Costa-Neto CM, Fernandes JPS. Corrêa MF, et al. Among authors: simoes sc. Front Pharmacol. 2017 Nov 14;8:825. doi: 10.3389/fphar.2017.00825. eCollection 2017. Front Pharmacol. 2017. PMID: 29184503 Free PMC article.