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Page 1
β-III-spectrin N-terminus is required for high-affinity actin binding and SCA5 neurotoxicity.
Sci Rep. 2022 Feb 2;12(1):1726. doi: 10.1038/s41598-022-05762-2.
Sci Rep. 2022.
PMID: 35110634
Free PMC article.
Novel drug discovery platform for spinocerebellar ataxia, using fluorescence technology targeting β-III-spectrin.
Rebbeck RT, Andrick AK, Denha SA, Svensson B, Guhathakurta P, Thomas DD, Hays TS, Avery AW.
Rebbeck RT, et al. Among authors: denha sa.
J Biol Chem. 2021 Jan-Jun;296:100215. doi: 10.1074/jbc.RA120.015417. Epub 2020 Dec 24.
J Biol Chem. 2021.
PMID: 33839680
Free PMC article.
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Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5.
Guhathakurta P, Rebbeck RT, Denha SA, Keller AR, Carter AL, Atang AE, Svensson B, Thomas DD, Hays TS, Avery AW.
Guhathakurta P, et al. Among authors: denha sa.
J Biol Chem. 2023 Mar;299(3):102956. doi: 10.1016/j.jbc.2023.102956. Epub 2023 Jan 31.
J Biol Chem. 2023.
PMID: 36731793
Free PMC article.
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Increased Actin Binding Is a Shared Molecular Consequence of Numerous SCA5 Mutations in β-III-Spectrin.
Atang AE, Keller AR, Denha SA, Avery AW.
Atang AE, et al. Among authors: denha sa.
Cells. 2023 Aug 19;12(16):2100. doi: 10.3390/cells12162100.
Cells. 2023.
PMID: 37626910
Free PMC article.
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Increased actin binding is a shared molecular consequence of numerous spinocerebellar ataxia mutations in β-III-spectrin.
Atang AE, Keller AR, Denha SA, Avery AW.
Atang AE, et al. Among authors: denha sa.
bioRxiv [Preprint]. 2023 Apr 10:2023.02.20.529285. doi: 10.1101/2023.02.20.529285.
bioRxiv. 2023.
PMID: 36865188
Free PMC article.
Updated.
Preprint.
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