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Individual Patient Data Meta-Analysis of FOLFOXIRI Plus Bevacizumab Versus Doublets Plus Bevacizumab as Initial Therapy of Unresectable Metastatic Colorectal Cancer.
Cremolini C, Antoniotti C, Stein A, Bendell J, Gruenberger T, Rossini D, Masi G, Ongaro E, Hurwitz H, Falcone A, Schmoll HJ, Di Maio M. Cremolini C, et al. J Clin Oncol. 2020 Aug 20:JCO2001225. doi: 10.1200/JCO.20.01225. Online ahead of print. J Clin Oncol. 2020. PMID: 32816630 Free article.
PURPOSE: A proper estimation of the magnitude of the overall survival (OS) benefit from infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) plus bevacizumab versus doublets + bevacizumab is lacking because all trials that have investigated this regimen ha …
PURPOSE: A proper estimation of the magnitude of the overall survival (OS) benefit from infusional fluorouracil, leucovorin, oxaliplatin, an …
Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing.
Ptashkin RN, Ewalt MD, Jayakumaran G, Kiecka I, Bowman AS, Yao J, Casanova J, Lin YD, Petrova-Drus K, Mohanty AS, Bacares R, Benhamida J, Rana S, Razumova A, Vanderbilt C, Balakrishnan Rema A, Rijo I, Son-Garcia J, de Bruijn I, Zhu M, Lachhander S, Wang W, Haque MS, Seshan VE, Wang J, Liu Y, Nafa K, Borsu L, Zhang Y, Aypar U, Suehnholz SP, Chakravarty D, Park JH, Abdel-Wahab O, Mato AR, Xiao W, Roshal M, Yabe M, Batlevi CL, Giralt S, Salles G, Rampal R, Tallman M, Stein EM, Younes A, Levine RL, Perales MA, van den Brink MRM, Dogan A, Ladanyi M, Berger MF, Brannon AR, Benayed R, Zehir A, Arcila ME. Ptashkin RN, et al. Nat Commun. 2023 Oct 28;14(1):6895. doi: 10.1038/s41467-023-42585-9. Nat Commun. 2023. PMID: 37898613 Free PMC article.
We highlight patterns of mutations, copy number alterations, and mutation signatures in a broad set of myeloid and lymphoid neoplasms. We also demonstrate the power of appropriate matching to make definitive somatic calls, including in patients who have undergone allogenei …
We highlight patterns of mutations, copy number alterations, and mutation signatures in a broad set of myeloid and lymphoid neoplasms. We al …
Correction to Maheu et al. (2023).
[No authors listed] [No authors listed] Health Psychol. 2023 Sep;42(9):667. doi: 10.1037/hea0001317. Epub 2023 Jul 13. Health Psychol. 2023. PMID: 37439750
Ramanakumar, Frederic Lamonde, Monique Lefebvre, Christina Tomei, Brittany Mutsaers, Scott Secord, Joanne Power, Nancy Drummond, Maude Hebert and Rajvi J. Wani (Health Psychology, 2023[Mar], Vol 42[3], 182-194). ...METHOD: One hundred and sixty-four women with clinical lev …
Ramanakumar, Frederic Lamonde, Monique Lefebvre, Christina Tomei, Brittany Mutsaers, Scott Secord, Joanne Power, Nancy Drummond, Maud …
Paenibacillus spp infection among infants with postinfectious hydrocephalus in Uganda: an observational case-control study.
Morton SU, Hehnly C, Burgoine K, Ssentongo P, Ericson JE, Kumar MS, Hagmann C, Fronterre C, Smith J, Movassagh M, Streck N, Bebell LM, Bazira J, Kumbakumba E, Bajunirwe F, Mulondo R, Mbabazi-Kabachelor E, Nsubuga BK, Natukwatsa D, Nalule E, Magombe J, Erickson T, Ngonzi J, Ochora M, Olupot-Olupot P, Onen J, Ssenyonga P, Mugamba J, Warf BC, Kulkarni AV, Lane J, Whalen AJ, Zhang L, Sheldon K, Meier FA, Kiwanuka J, Broach JR, Paulson JN, Schiff SJ. Morton SU, et al. Lancet Microbe. 2023 Aug;4(8):e601-e611. doi: 10.1016/S2666-5247(23)00106-4. Epub 2023 Jun 19. Lancet Microbe. 2023. PMID: 37348522 Free PMC article.
Bacillus Calmette-Guérin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial.
Pittet LF, Moore CL, McDonald E, Barry S, Bonten M, Campbell J, Croda J, Dalcolmo M, Davidson A, Douglas MW, Gardiner K, Gwee A, Jardim B, Lacerda MVG, Lucas M, Lynn DJ, Manning L, de Oliveira RD, Perrett KP, Prat-Aymerich C, Richmond PC, Rocha JL, Rodriguez-Baño J, Warris A, Wood NJ, Messina NL, Curtis N; BRACE Trial Consortium Group. Pittet LF, et al. EClinicalMedicine. 2023 Sep 11;64:102203. doi: 10.1016/j.eclinm.2023.102203. eCollection 2023 Oct. EClinicalMedicine. 2023. PMID: 37719417 Free PMC article.
FINDINGS: Between March 30, 2020 and February 18, 2021, 84 individuals with frequent recurrent cold sores were randomly assigned to BCG (n = 38) or control (n = 46). The average time to first cold-sore recurrence was 1.55 months longer in the BCG group (95% CI 0.27- …
FINDINGS: Between March 30, 2020 and February 18, 2021, 84 individuals with frequent recurrent cold sores were randomly assigned to BCG ( …
Lessons for achieving health equity comparing Aotearoa/New Zealand and the United States.
Chin MH, King PT, Jones RG, Jones B, Ameratunga SN, Muramatsu N, Derrett S. Chin MH, et al. Health Policy. 2018 Aug;122(8):837-853. doi: 10.1016/j.healthpol.2018.05.001. Epub 2018 Jun 28. Health Policy. 2018. PMID: 29961558 Free PMC article. Review.
To authentically commit to achieving health equity, nations should: 1) Explicitly design quality of care and payment policies to achieve equity, holding the healthcare system accountable through public monitoring and evaluation, and supporting with adequate resources; 2) Address …
To authentically commit to achieving health equity, nations should: 1) Explicitly design quality of care and payment policies to achieve equ …
Evaluation of a liquid-phase plasma discharge process for ammonia oxidation in wastewater: Process optimization and kinetic modeling.
Aka RJN, Wu S, Mohotti D, Bashir MA, Nasir A. Aka RJN, et al. Water Res. 2022 Oct 1;224:119107. doi: 10.1016/j.watres.2022.119107. Epub 2022 Sep 13. Water Res. 2022. PMID: 36122445
The gas-flow rate and power input were found to be significant factors affecting the removal efficiency of NH(3)N, whereas the initial concentration of NH(3)N played a vital role in determining the energy efficiency of the process. Under the optimal condition …
The gas-flow rate and power input were found to be significant factors affecting the removal efficiency of NH(3)N, whereas the …
Preventing sepsis; how can artificial intelligence inform the clinical decision-making process? A systematic review.
Hassan N, Slight R, Weiand D, Vellinga A, Morgan G, Aboushareb F, Slight SP. Hassan N, et al. Int J Med Inform. 2021 Jun;150:104457. doi: 10.1016/j.ijmedinf.2021.104457. Epub 2021 Apr 10. Int J Med Inform. 2021. PMID: 33878596 Review.
CONCLUSION: The type of predictors influenced the predictive power and predictive timeframe of the developed machine learning algorithm. ...
CONCLUSION: The type of predictors influenced the predictive power and predictive timeframe of the developed machine learning algorit …
Time-frequency analyses of repetition suppression and change detection in children with neurofibromatosis type 1.
Lalancette E, Charlebois-Poirier AR, Agbogba K, Knoth IS, Côté V, Perreault S, Lippé S. Lalancette E, et al. Brain Res. 2023 Nov 1;1818:148512. doi: 10.1016/j.brainres.2023.148512. Epub 2023 Jul 25. Brain Res. 2023. PMID: 37499730
In this study, we examined the repetition suppression (RS) and change detection responses in children with NF1 (n = 36) and neurotypical controls (n = 41) aged from 4 to 13 years old, using a simple sequence of vowels. ...Children with NF1 showed preserved RS, but i …
In this study, we examined the repetition suppression (RS) and change detection responses in children with NF1 (n = 36) and neurotypi …
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