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Kynurenine pathway is altered in patients with SLE and associated with severe fatigue.
Åkesson K, Pettersson S, Ståhl S, Surowiec I, Hedenström M, Eketjäll S, Trygg J, Jakobsson PJ, Gunnarsson I, Svenungsson E, Idborg H. Åkesson K, et al. Among authors: stahl s. Lupus Sci Med. 2018 May 23;5(1):e000254. doi: 10.1136/lupus-2017-000254. eCollection 2018. Lupus Sci Med. 2018. PMID: 29868176 Free PMC article.
TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Thornton P, Sevalle J, Deery MJ, Fraser G, Zhou Y, Ståhl S, Franssen EH, Dodd RB, Qamar S, Gomez Perez-Nievas B, Nicol LS, Eketjäll S, Revell J, Jones C, Billinton A, St George-Hyslop PH, Chessell I, Crowther DC. Thornton P, et al. Among authors: stahl s. EMBO Mol Med. 2017 Oct;9(10):1366-1378. doi: 10.15252/emmm.201707673. EMBO Mol Med. 2017. PMID: 28855301 Free PMC article.