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Page 1
Towards small molecule inhibitors of mono-ADP-ribosyltransferases.
Ekblad T, Lindgren AE, Andersson CD, Caraballo R, Thorsell AG, Karlberg T, Spjut S, Linusson A, Schüler H, Elofsson M. Ekblad T, et al. Among authors: spjut s. Eur J Med Chem. 2015 May 5;95:546-51. doi: 10.1016/j.ejmech.2015.03.067. Epub 2015 Apr 1. Eur J Med Chem. 2015. PMID: 25847771 Free article.
PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.
Lindgren AE, Karlberg T, Thorsell AG, Hesse M, Spjut S, Ekblad T, Andersson CD, Pinto AF, Weigelt J, Hottiger MO, Linusson A, Elofsson M, Schüler H. Lindgren AE, et al. Among authors: spjut s. ACS Chem Biol. 2013 Aug 16;8(8):1698-703. doi: 10.1021/cb4002014. Epub 2013 Jun 25. ACS Chem Biol. 2013. PMID: 23742272
Discovery of ligands for ADP-ribosyltransferases via docking-based virtual screening.
Andersson CD, Karlberg T, Ekblad T, Lindgren AE, Thorsell AG, Spjut S, Uciechowska U, Niemiec MS, Wittung-Stafshede P, Weigelt J, Elofsson M, Schüler H, Linusson A. Andersson CD, et al. Among authors: spjut s. J Med Chem. 2012 Sep 13;55(17):7706-18. doi: 10.1021/jm300746d. Epub 2012 Aug 20. J Med Chem. 2012. PMID: 22823910
Small-molecule screening using a whole-cell viral replication reporter gene assay identifies 2-{[2-(benzoylamino)benzoyl]amino}-benzoic acid as a novel antiadenoviral compound.
Andersson EK, Strand M, Edlund K, Lindman K, Enquist PA, Spjut S, Allard A, Elofsson M, Mei YF, Wadell G. Andersson EK, et al. Among authors: spjut s. Antimicrob Agents Chemother. 2010 Sep;54(9):3871-7. doi: 10.1128/AAC.00203-10. Epub 2010 Jun 28. Antimicrob Agents Chemother. 2010. PMID: 20585112 Free PMC article.