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1946 3
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1951 6
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1953 3
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1955 2
1956 3
1957 8
1958 5
1959 7
1960 6
1961 4
1962 9
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1964 22
1965 23
1966 15
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1978 46
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1980 32
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1987 69
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The following term was not found in PubMed: Sanghati
Page 1
Did you mean sanghani saha (6 results)?
The SAHA syndrome.
Orfanos CE, Adler YD, Zouboulis CC. Orfanos CE, et al. Horm Res. 2000;54(5-6):251-8. doi: 10.1159/000053267. Horm Res. 2000. PMID: 11595813 Review.
The presence of seborrhoea, acne, hirsutism and alopecia in women has first been summarized as SAHA syndrome in 1982 and can be associated with polycystic ovary syndrome, cystic mastitis, obesity and infertility. ...Treatment will target the etiology, whereas the managemen …
The presence of seborrhoea, acne, hirsutism and alopecia in women has first been summarized as SAHA syndrome in 1982 and can be assoc …
Vorinostat (SAHA) and Breast Cancer: An Overview.
Wawruszak A, Borkiewicz L, Okon E, Kukula-Koch W, Afshan S, Halasa M. Wawruszak A, et al. Cancers (Basel). 2021 Sep 19;13(18):4700. doi: 10.3390/cancers13184700. Cancers (Basel). 2021. PMID: 34572928 Free PMC article. Review.
Vorinostat (SAHA), an inhibitor of class I and II of histone deacetylases, is the first histone deacetylase inhibitor (HDI) approved for the treatment of cutaneous T-cell lymphoma in 2006. ...This manuscript analyzes preclinical and clinical trials data of SAHA, app …
Vorinostat (SAHA), an inhibitor of class I and II of histone deacetylases, is the first histone deacetylase inhibitor (HDI) approved …
Histone Deacetylase Inhibitor (SAHA) Reduces Mortality in an Endotoxemia Mouse Model by Suppressing Glycolysis.
Wu Y, He Y, Liu C, Ehle C, Iyer-Bierhoff A, Liu B, Heinzel T, Xing S. Wu Y, et al. Int J Mol Sci. 2023 Aug 4;24(15):12448. doi: 10.3390/ijms241512448. Int J Mol Sci. 2023. PMID: 37569823 Free PMC article.
Histone deacetylase inhibitors (HDACi), such as suberoylanilide hydroxamic acid (SAHA), have been proposed as potent anti-inflammatory agents for treating inflammatory diseases. ...Overall, our study provides insights into the mechanism underlying SAHA's therapeutic …
Histone deacetylase inhibitors (HDACi), such as suberoylanilide hydroxamic acid (SAHA), have been proposed as potent anti-inflammator …
SAHA could inhibit TGF-beta1/p38 pathway in MI-induced cardiac fibrosis through DUSP4 overexpression.
Wang K, Tang R, Wang S, Wang W, Zhang K, Li J, Li P, Tang YD. Wang K, et al. Heart Vessels. 2022 Jan;37(1):152-160. doi: 10.1007/s00380-021-01900-4. Epub 2021 Jul 8. Heart Vessels. 2022. PMID: 34236463 Free PMC article.
Mice with MI-induced cardiac fibrosis were treated with SAHA by intraperitoneal injection and their cardiac function was improved after SAHA treatment. ...Our findings may substantiate SAHA as a promising treatment for MI-induced cardiac fibrosis....
Mice with MI-induced cardiac fibrosis were treated with SAHA by intraperitoneal injection and their cardiac function was improved aft …
The combination of the HDAC1 inhibitor SAHA and doxorubicin has synergic efficacy in triple negative breast cancer in vivo.
Pang Y, Shi R, Chan L, Lu Y, Zhu D, Liu T, Yan M, Wang Y, Wang W. Pang Y, et al. Pharmacol Res. 2023 Oct;196:106926. doi: 10.1016/j.phrs.2023.106926. Epub 2023 Sep 15. Pharmacol Res. 2023. PMID: 37716547 Free article.
Vorinostat (SAHA) is a histone deacetylase inhibitor that exerts its effects through epigenetic regulation. ...Overall, the combination of DOX and SAHA presents a promising avenue for innovative combination chemotherapy in the context of TNBC....
Vorinostat (SAHA) is a histone deacetylase inhibitor that exerts its effects through epigenetic regulation. ...Overall, the combinati …
Suberoylanilide Hydroxamic Acid (SAHA) Is a Driver Molecule of Neuroplasticity: Implication for Neurological Diseases.
Verrillo L, Di Palma R, de Bellis A, Drongitis D, Miano MG. Verrillo L, et al. Biomolecules. 2023 Aug 24;13(9):1301. doi: 10.3390/biom13091301. Biomolecules. 2023. PMID: 37759701 Free PMC article. Review.
One of the epi-drivers priming this process is suberoylanilide hydroxamic acid (SAHA or Vorinostat), a pan-histone deacetylase inhibitor that modulates and promotes neuroplasticity in healthy and disease conditions. ...In particular, we outline studies regarding neurodevel …
One of the epi-drivers priming this process is suberoylanilide hydroxamic acid (SAHA or Vorinostat), a pan-histone deacetylase inhibi …
SAHA is neuroprotective in in vitro and in situ models of retinitis pigmentosa.
Perron NR, Nasarre C, Bandyopadhyay M, Beeson CC, Rohrer B. Perron NR, et al. Mol Vis. 2021 Apr 2;27:151-160. eCollection 2021. Mol Vis. 2021. PMID: 33907370 Free PMC article.
Here we tested the efficacy of SAHA for its ability to protect photoreceptors in in-vitro and in-situ models of RP. ...The protective effects of SAHA were also observed on photoreceptor cell survival in whole retinal organ explants of the rd1 mouse. ...
Here we tested the efficacy of SAHA for its ability to protect photoreceptors in in-vitro and in-situ models of RP. ...The protective …
Phosphorus containing analogues of SAHA as inhibitors of HDACs.
Pun MD, Wu HH, Olatunji FP, Kesic BN, Peters JW, Berkman CE. Pun MD, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1315-1319. doi: 10.1080/14756366.2022.2063281. J Enzyme Inhib Med Chem. 2022. PMID: 35514164 Free PMC article.
In this work, phosphorus-based SAHA analogues were synthesised to assess their zinc-binding effectiveness compared to the hydroxamic acid of SAHA. ...HDAC inhibition assays demonstrated that these phosphorus-based SAHA analogs exhibited slow binding to HDACs …
In this work, phosphorus-based SAHA analogues were synthesised to assess their zinc-binding effectiveness compared to the hydroxamic …
Discovery and development of SAHA as an anticancer agent.
Marks PA. Marks PA. Oncogene. 2007 Feb 26;26(9):1351-6. doi: 10.1038/sj.onc.1210204. Oncogene. 2007. PMID: 17322921 Review.
It was discovered that SAHA inhibits the activity of histone deacetylases (HDACs), including all 11 known human class I and class II HDACs. ...A new drug application has been approved for SAHA (vorinostat) treatment of cutaneous T-cell lymphoma....
It was discovered that SAHA inhibits the activity of histone deacetylases (HDACs), including all 11 known human class I and class II …
SAHA Overcomes 5-FU Resistance in IFIT2-Depleted Oral Squamous Cell Carcinoma Cells.
Regmi P, Lai KC, Liu CJ, Lee TC. Regmi P, et al. Cancers (Basel). 2020 Nov 26;12(12):3527. doi: 10.3390/cancers12123527. Cancers (Basel). 2020. PMID: 33256074 Free PMC article.
In conclusion, IFIT2 knockdown enhances TS expression, which mediates 5-FU resistance, and SAHA pretreatment suppresses TS expression and hence sensitizes cells to 5-FU. SAHA will be an effective strategy for the treatment of OSCC patients with 5-FU resistance....
In conclusion, IFIT2 knockdown enhances TS expression, which mediates 5-FU resistance, and SAHA pretreatment suppresses TS expression …
21,820 results
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