The effects of the toxic cyanobacterium Limnothrix (strain AC0243) on Bufo marinus larvae

Toxins (Basel). 2014 Mar 6;6(3):1021-35. doi: 10.3390/toxins6031021.

Abstract

Limnothrix (strain AC0243) is a cyanobacterium, which has only recently been identified as toxin producing. Under laboratory conditions, Bufo marinus larvae were exposed to 100,000 cells mL(-1) of Limnothrix (strain AC0243) live cultures for seven days. Histological examinations were conducted post mortem and revealed damage to the notochord, eyes, brain, liver, kidney, pancreas, gastrointestinal tract, and heart. The histopathological results highlight the toxicological impact of this strain, particularly during developmental stages. Toxicological similarities to β-N-Methylamino-L-alanine are discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacterial Toxins / toxicity*
  • Brain / drug effects
  • Brain / growth & development
  • Brain / pathology
  • Bufo marinus / growth & development*
  • Cyanobacteria*
  • Eye / drug effects
  • Eye / growth & development
  • Eye / pathology
  • Gastrointestinal Tract / drug effects
  • Gastrointestinal Tract / growth & development
  • Gastrointestinal Tract / pathology
  • Heart / drug effects
  • Heart / growth & development
  • Kidney / drug effects
  • Kidney / growth & development
  • Kidney / pathology
  • Larva / drug effects
  • Larva / growth & development
  • Liver / drug effects
  • Liver / growth & development
  • Liver / pathology
  • Myocardium / pathology
  • Notochord / drug effects
  • Notochord / growth & development
  • Notochord / pathology
  • Pancreas / drug effects
  • Pancreas / growth & development
  • Pancreas / pathology

Substances

  • Bacterial Toxins