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2020 3
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Design, Molecular Docking, Synthesis, Anticancer and Anti-Hyperglycemic Assessments of Thiazolidine-2,4-diones Bearing Sulfonylthiourea Moieties as Potent VEGFR-2 Inhibitors and PPARγ Agonists.
Abdelgawad MA, El-Adl K, El-Hddad SSA, Elhady MM, Saleh NM, Khalifa MM, Khedr F, Alswah M, Nayl AA, Ghoneim MM, Abd El-Sattar NEA. Abdelgawad MA, et al. Among authors: el hddad ssa. Pharmaceuticals (Basel). 2022 Feb 14;15(2):226. doi: 10.3390/ph15020226. Pharmaceuticals (Basel). 2022. PMID: 35215339 Free PMC article.
Five and six membered heterocyclic rings endowed with azobenzene as dual EGFRT790M and VEGFR-2 inhibitors: design, synthesis, in silico ADMET profile, molecular docking, dynamic simulation and anticancer evaluations.
Anwer KE, El-Hddad SSA, Abd El-Sattar NEA, El-Morsy A, Khedr F, Mohamady S, Keshek DE, Salama SA, El-Adl K, Hanafy NS. Anwer KE, et al. Among authors: el hddad ssa. RSC Adv. 2023 Dec 4;13(50):35321-35338. doi: 10.1039/d3ra06614b. eCollection 2023 Nov 30. RSC Adv. 2023. PMID: 38053688 Free PMC article.
Design, synthesis, molecular docking, anticancer evaluations, and in silico pharmacokinetic studies of novel 5-[(4-chloro/2,4-dichloro)benzylidene]thiazolidine-2,4-dione derivatives as VEGFR-2 inhibitors.
El-Adl K, El-Helby AA, Sakr H, Ayyad RR, Mahdy HA, Nasser M, Abulkhair HS, El-Hddad SSA. El-Adl K, et al. Among authors: el hddad ssa. Arch Pharm (Weinheim). 2021 Feb;354(2):e2000279. doi: 10.1002/ardp.202000279. Epub 2020 Oct 19. Arch Pharm (Weinheim). 2021. PMID: 33073374