Dual view deep learning for enhanced breast cancer screening using mammography

Sci Rep. 2024 Feb 15;14(1):3839. doi: 10.1038/s41598-023-50797-8.

Abstract

Breast cancer has the highest incidence rate among women in Ethiopia compared to other types of cancer. Unfortunately, many cases are detected at a stage where a cure is delayed or not possible. To address this issue, mammography-based screening is widely accepted as an effective technique for early detection. However, the interpretation of mammography images requires experienced radiologists in breast imaging, a resource that is limited in Ethiopia. In this research, we have developed a model to assist radiologists in mass screening for breast abnormalities and prioritizing patients. Our approach combines an ensemble of EfficientNet-based classifiers with YOLOv5, a suspicious mass detection method, to identify abnormalities. The inclusion of YOLOv5 detection is crucial in providing explanations for classifier predictions and improving sensitivity, particularly when the classifier fails to detect abnormalities. To further enhance the screening process, we have also incorporated an abnormality detection model. The classifier model achieves an F1-score of 0.87 and a sensitivity of 0.82. With the addition of suspicious mass detection, sensitivity increases to 0.89, albeit at the expense of a slightly lower F1-score of 0.79.

MeSH terms

  • Breast Neoplasms* / diagnostic imaging
  • Breast Neoplasms* / epidemiology
  • Deep Learning*
  • Early Detection of Cancer / methods
  • Female
  • Humans
  • Mammography / methods
  • Mass Screening