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Page 1
A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells.
Nat Biotechnol. 2021 Jan;39(1):47-55. doi: 10.1038/s41587-020-0741-7. Epub 2020 Nov 16.
Nat Biotechnol. 2021.
PMID: 33199875
Free PMC article.
Altered cleavage of human factor VIII at the B-domain and acidic region 3 interface enhances expression after gene therapy in hemophilia A mice.
Nguyen GN, Lindgren JR, Seleme MC, Kafle S, Zander CB, Zheng XL, Sabatino DE.
Nguyen GN, et al. Among authors: kafle s.
J Thromb Haemost. 2023 Aug;21(8):2101-2113. doi: 10.1016/j.jtha.2023.04.012. Epub 2023 Apr 18.
J Thromb Haemost. 2023.
PMID: 37080538
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mRNA-LNP vaccine-induced CD8+ T cells protect mice from lethal SARS-CoV-2 infection in the absence of specific antibodies.
Montoya B, Melo-Silva CR, Tang L, Kafle S, Lidskiy P, Bajusz C, Vadovics M, Muramatsu H, Abraham E, Lipinszki Z, Chatterjee D, Scher G, Benitez J, Sung MMH, Tam YK, Catanzaro NJ, Schäfer A, Andino R, Baric RS, Martinez DR, Pardi N, Sigal LJ.
Montoya B, et al. Among authors: kafle s.
Mol Ther. 2024 Apr 11:S1525-0016(24)00236-3. doi: 10.1016/j.ymthe.2024.04.019. Online ahead of print.
Mol Ther. 2024.
PMID: 38605519
Free article.
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Resistance To Poxvirus Lethality Does Not Require the Necroptosis Proteins RIPK3 or MLKL.
Montoya B, Knudson CJ, Melo-Silva CR, Tang L, Kafle S, Sigal LJ.
Montoya B, et al. Among authors: kafle s.
J Virol. 2023 Feb 28;97(2):e0194522. doi: 10.1128/jvi.01945-22. Epub 2023 Jan 18.
J Virol. 2023.
PMID: 36651749
Free PMC article.
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Multiple and Consecutive Genome Editing Using i-GONAD and Breeding Enrichment Facilitates the Production of Genetically Modified Mice.
Melo-Silva CR, Knudson CJ, Tang L, Kafle S, Springer LE, Choi J, Snyder CM, Wang Y, Kim SV, Sigal LJ.
Melo-Silva CR, et al. Among authors: kafle s.
Cells. 2023 May 8;12(9):1343. doi: 10.3390/cells12091343.
Cells. 2023.
PMID: 37174743
Free PMC article.
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