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Page 1
In vitro and computational investigations of novel synthetic carboxamide-linked pyridopyrrolopyrimidines with potent activity as SARS-CoV-2-MPro inhibitors.
Aljuhani A, Ahmed HEA, Ihmaid SK, Omar AM, Althagfan SS, Alahmadi YM, Ahmad I, Patel H, Ahmed S, Almikhlafi MA, El-Agrody AM, Zayed MF, Turkistani SA, Abulkhair SH, Almaghrabi M, Salama SA, Al-Karmalawy AA, Abulkhair HS. Aljuhani A, et al. Among authors: ihmaid sk. RSC Adv. 2022 Sep 22;12(41):26895-26907. doi: 10.1039/d2ra04015h. eCollection 2022 Sep 16. RSC Adv. 2022. PMID: 36320844 Free PMC article.
Exploring the dual effect of novel 1,4-diarylpyranopyrazoles as antiviral and anti-inflammatory for the management of SARS-CoV-2 and associated inflammatory symptoms.
Malebari AM, E A Ahmed H, Ihmaid SK, Omar AM, Muhammad YA, Althagfan SS, Aljuhani N, A A El-Sayed AA, Halawa AH, El-Tahir HM, Turkistani SA, Almaghrabi M, K B Aljohani A, El-Agrody AM, Abulkhair HS. Malebari AM, et al. Among authors: ihmaid sk. Bioorg Chem. 2023 Jan;130:106255. doi: 10.1016/j.bioorg.2022.106255. Epub 2022 Nov 17. Bioorg Chem. 2023. PMID: 36403336 Free PMC article.
Design and Synthesis of Benzene Homologues Tethered with 1,2,4-Triazole and 1,3,4-Thiadiazole Motifs Revealing Dual MCF-7/HepG2 Cytotoxic Activity with Prominent Selectivity via Histone Demethylase LSD1 Inhibitory Effect.
Alsehli M, Aljuhani A, Ihmaid SK, El-Messery SM, Othman DIA, El-Sayed AAA, Ahmed HEA, Rezki N, Aouad MR. Alsehli M, et al. Among authors: ihmaid sk. Int J Mol Sci. 2022 Aug 8;23(15):8796. doi: 10.3390/ijms23158796. Int J Mol Sci. 2022. PMID: 35955929 Free PMC article.
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations.
Musa A, Ihmaid SK, Hughes DL, Said MA, Abulkhair HS, El-Ghorab AH, Abdelgawad MA, Shalaby K, Shaker ME, Alharbi KS, Alotaibi NH, Kays DL, Taylor LJ, Parambi DGT, Alzarea SI, Al-Karmalawy AA, Ahmed HEA, El-Agrody AM. Musa A, et al. Among authors: ihmaid sk. J Biomol Struct Dyn. 2023;41(21):12411-12425. doi: 10.1080/07391102.2023.2167000. Epub 2023 Jan 20. J Biomol Struct Dyn. 2023. PMID: 36661285