A highly efficient bismuth salts-catalyzed route for the synthesis of α-aminophosphonates

Molecules. 2010 Nov 12;15(11):8205-13. doi: 10.3390/molecules15118205.

Abstract

A convenient synthesis of different types of α-amino phosphonates via one-pot solvent-free three component reactions of aldehydes, amines and phosphites catalyzed by bismuth salts has been investigated. Bismuth triflate is found to be the most effective catalyst for this reaction.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aldehydes / chemistry
  • Bismuth / chemistry*
  • Catalysis
  • Imines / chemistry
  • Molecular Structure
  • Organophosphonates / chemical synthesis*
  • Organophosphonates / chemistry*
  • Phosphites / chemistry

Substances

  • Aldehydes
  • Imines
  • Organophosphonates
  • Phosphites
  • Bismuth