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HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Hoefflin R, Harlander S, Schäfer S, Metzger P, Kuo F, Schönenberger D, Adlesic M, Peighambari A, Seidel P, Chen CY, Consenza-Contreras M, Jud A, Lahrmann B, Grabe N, Heide D, Uhl FM, Chan TA, Duyster J, Zeiser R, Schell C, Heikenwalder M, Schilling O, Hakimi AA, Boerries M, Frew IJ. Hoefflin R, et al. Among authors: harlander s. Nat Commun. 2020 Aug 17;11(1):4111. doi: 10.1038/s41467-020-17873-3. Nat Commun. 2020. PMID: 32807776 Free PMC article.
Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma.
Hoefflin R, Harlander S, Abhari BA, Peighambari A, Adlesic M, Seidel P, Zodel K, Haug S, Göcmen B, Li Y, Lahrmann B, Grabe N, Heide D, Boerries M, Köttgen A, Heikenwalder M, Frew IJ. Hoefflin R, et al. Among authors: harlander s. Cancers (Basel). 2021 Sep 25;13(19):4801. doi: 10.3390/cancers13194801. Cancers (Basel). 2021. PMID: 34638286 Free PMC article.
Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice.
Albers J, Rajski M, Schönenberger D, Harlander S, Schraml P, von Teichman A, Georgiev S, Wild PJ, Moch H, Krek W, Frew IJ. Albers J, et al. Among authors: harlander s. EMBO Mol Med. 2013 Jun;5(6):949-64. doi: 10.1002/emmm.201202231. Epub 2013 Apr 22. EMBO Mol Med. 2013. PMID: 23606570 Free PMC article.
Chicken ovalbumin upstream promoter transcription factor II regulates renin gene expression.
Mayer S, Roeser M, Lachmann P, Ishii S, Suh JM, Harlander S, Desch M, Brunssen C, Morawietz H, Tsai SY, Tsai MJ, Hohenstein B, Hugo C, Todorov VT. Mayer S, et al. Among authors: harlander s. J Biol Chem. 2012 Jul 13;287(29):24483-91. doi: 10.1074/jbc.M111.329474. Epub 2012 May 29. J Biol Chem. 2012. PMID: 22645148 Free PMC article.