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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1977 1
1981 2
1982 1
1984 3
1986 1
1987 1
1988 5
1989 1
1990 7
1991 5
1992 4
1993 4
1994 6
1995 5
1996 12
1997 9
1998 13
1999 9
2000 7
2001 5
2002 7
2003 5
2004 5
2005 5
2006 7
2007 10
2008 4
2009 6
2010 9
2011 8
2012 8
2013 19
2014 40
2015 42
2016 42
2017 38
2018 38
2019 40
2020 50
2021 60
2022 38
2023 48
2024 19

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583 results

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Page 1
Bacteria induce skin regeneration via IL-1β signaling.
Wang G, Sweren E, Liu H, Wier E, Alphonse MP, Chen R, Islam N, Li A, Xue Y, Chen J, Park S, Chen Y, Lee S, Wang Y, Wang S, Archer NK, Andrews W, Kane MA, Dare E, Reddy SK, Hu Z, Grice EA, Miller LS, Garza LA. Wang G, et al. Cell Host Microbe. 2021 May 12;29(5):777-791.e6. doi: 10.1016/j.chom.2021.03.003. Epub 2021 Apr 1. Cell Host Microbe. 2021. PMID: 33798492 Free PMC article.
WIHN levels and stem cell markers correlate with bacterial counts, being lowest in germ-free (GF), intermediate in conventional specific pathogen-free (SPF), and highest in wild-type mice, even those infected with pathogenic Staphylococcus aureus. ...
WIHN levels and stem cell markers correlate with bacterial counts, being lowest in germ-free (GF), intermediate in conventional specific pat …
ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts.
Enzan N, Matsushima S, Ikeda S, Okabe K, Ishikita A, Yamamoto T, Sada M, Miyake R, Tsutsui Y, Nishimura R, Toyohara T, Ikeda Y, Shojima Y, Miyamoto HD, Tadokoro T, Ikeda M, Abe K, Ide T, Kinugawa S, Tsutsui H. Enzan N, et al. Circ Res. 2023 Apr 28;132(9):1110-1126. doi: 10.1161/CIRCRESAHA.122.322227. Epub 2023 Mar 28. Circ Res. 2023. PMID: 36974722 Free PMC article.
METHODS: mtDNA was administrated into isolated cardiomyocytes. Myocardial infarctionwas conducted in wild type and ZBP1 knockout mice. RESULTS: We here found that, unlike in macrophages, ZBP1 knockdown unexpectedly exacerbated mtDNA-induced inflammation such as increases i …
METHODS: mtDNA was administrated into isolated cardiomyocytes. Myocardial infarctionwas conducted in wild type and ZBP1 knockout mice …
m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis.
Cieśla M, Ngoc PCT, Muthukumar S, Todisco G, Madej M, Fritz H, Dimitriou M, Incarnato D, Hellström-Lindberg E, Bellodi C. Cieśla M, et al. Mol Cell. 2023 Apr 6;83(7):1165-1179.e11. doi: 10.1016/j.molcel.2023.02.024. Epub 2023 Mar 20. Mol Cell. 2023. PMID: 36944332 Free article.
Although tumorigenic SF3B1 mutations have been extensively characterized, the role of "non-mutated" wild-type SF3B1 in cancer remains largely unresolved. Here, we identify a conserved epitranscriptomic program that steers SF3B1 levels to counteract leukemogenesis. ...
Although tumorigenic SF3B1 mutations have been extensively characterized, the role of "non-mutated" wild-type SF3B1 in cancer remains …
Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections.
Brandi P, Conejero L, Cueto FJ, Martínez-Cano S, Dunphy G, Gómez MJ, Relaño C, Saz-Leal P, Enamorado M, Quintas A, Dopazo A, Amores-Iniesta J, Del Fresno C, Nistal-Villán E, Ardavín C, Nieto A, Casanovas M, Subiza JL, Sancho D. Brandi P, et al. Cell Rep. 2022 Jan 4;38(1):110184. doi: 10.1016/j.celrep.2021.110184. Cell Rep. 2022. PMID: 34986349 Free PMC article.
Intranasal administration of MV130 provides protection against systemic candidiasis in wild-type and Rag1-deficient mice lacking functional lymphocytes, indicative of innate immune-mediated protection. ...
Intranasal administration of MV130 provides protection against systemic candidiasis in wild-type and Rag1-deficient mice lacking func …
Evolution of self-compatibility by a mutant S(m)-RNase in citrus.
Liang M, Cao Z, Zhu A, Liu Y, Tao M, Yang H, Xu Q Jr, Wang S, Liu J, Li Y, Chen C, Xie Z, Deng C, Ye J, Guo W, Xu Q, Xia R, Larkin RM, Deng X, Bosch M, Franklin-Tong VE, Chai L. Liang M, et al. Nat Plants. 2020 Feb;6(2):131-142. doi: 10.1038/s41477-020-0597-3. Epub 2020 Feb 13. Nat Plants. 2020. PMID: 32055045 Free PMC article.
Our data support the notion that citrus have a S locus comprising a S-RNase and several SLFs that fit the non-self-recognition model. We identify a predominant single nucleotide mutation, S(m)-RNase, in SC citrus, which provides a 'natural' loss of function. We show …
Our data support the notion that citrus have a S locus comprising a S-RNase and several SLFs that fit the non-self-recognition model. We ide …
Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution.
Goodyer WR, Beyersdorf BM, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM. Goodyer WR, et al. Circ Res. 2019 Aug 2;125(4):379-397. doi: 10.1161/CIRCRESAHA.118.314578. Epub 2019 Jul 9. Circ Res. 2019. PMID: 31284824 Free PMC article.
OBJECTIVE: Assess the transcriptional landscape of the entire CCS at single-cell resolution by single-cell RNA-sequencing within the developing mouse heart. METHODS AND RESULTS: Wild-type, embryonic day 16.5 mouse hearts (n=6 per zone) were harvested and 3 zones of microdi …
OBJECTIVE: Assess the transcriptional landscape of the entire CCS at single-cell resolution by single-cell RNA-sequencing within the develop …
Natural History, Quality of Life, and Outcome in Cardiac Transthyretin Amyloidosis.
Lane T, Fontana M, Martinez-Naharro A, Quarta CC, Whelan CJ, Petrie A, Rowczenio DM, Gilbertson JA, Hutt DF, Rezk T, Strehina SG, Caringal-Galima J, Manwani R, Sharpley FA, Wechalekar AD, Lachmann HJ, Mahmood S, Sachchithanantham S, Drage EPS, Jenner HD, McDonald R, Bertolli O, Calleja A, Hawkins PN, Gillmore JD. Lane T, et al. Circulation. 2019 Jul 2;140(1):16-26. doi: 10.1161/CIRCULATIONAHA.118.038169. Epub 2019 May 21. Circulation. 2019. PMID: 31109193
We sought to characterize the natural history of ATTR-CM and compare outcomes and quality of life among patients with acquired and hereditary forms of the disease. METHODS: We studied 711 patients with wild-type ATTR-CM, 205 with hereditary ATTR-CM associated with the V122 …
We sought to characterize the natural history of ATTR-CM and compare outcomes and quality of life among patients with acquired and hereditar …
RNA-Binding Protein LIN28a Regulates New Myocyte Formation in the Heart Through Long Noncoding RNA-H19.
Rigaud VOC, Hoy RC, Kurian J, Zarka C, Behanan M, Brosious I, Pennise J, Patel T, Wang T, Johnson J, Kraus LM, Mohsin S, Houser SR, Khan M. Rigaud VOC, et al. Circulation. 2023 Jan 24;147(4):324-337. doi: 10.1161/CIRCULATIONAHA.122.059346. Epub 2022 Oct 31. Circulation. 2023. PMID: 36314132 Free PMC article.
With the use of neonatal and adult cell culture systems and adult and Mosaic Analysis with Double Markers myocardial injury models in mice, the effect of LIN28a overexpression on cardiomyocyte cell cycle and metabolism was tested. Last, isolated adult cardiomyocytes from LIN28a a …
With the use of neonatal and adult cell culture systems and adult and Mosaic Analysis with Double Markers myocardial injury models in mice, …
In Vivo Base Editing of Scn5a Rescues Type 3 Long QT Syndrome in Mice.
Qi M, Ma S, Liu J, Liu X, Wei J, Lu WJ, Zhang S, Chang Y, Zhang Y, Zhong K, Yan Y, Zhu M, Song Y, Chen Y, Hao G, Wang J, Wang L, Lee AS, Chen X, Wang Y, Lan F. Qi M, et al. Circulation. 2024 Jan 23;149(4):317-329. doi: 10.1161/CIRCULATIONAHA.123.065624. Epub 2023 Nov 15. Circulation. 2024. PMID: 37965733
Carbachol administration induced Torsades de Pointes or ventricular tachycardia for homozygous T1307M mice (20%) but not for heterozygous or wild-type mice. A single intraperitoneal injection of AAV9-ABEmax at postnatal day 14 resulted in up to 99.20% Scn5a transcripts cor …
Carbachol administration induced Torsades de Pointes or ventricular tachycardia for homozygous T1307M mice (20%) but not for heterozygous or …
EXO1 protects BRCA1-deficient cells against toxic DNA lesions.
van de Kooij B, Schreuder A, Pavani R, Garzero V, Uruci S, Wendel TJ, van Hoeck A, San Martin Alonso M, Everts M, Koerse D, Callen E, Boom J, Mei H, Cuppen E, Luijsterburg MS, van Vugt MATM, Nussenzweig A, van Attikum H, Noordermeer SM. van de Kooij B, et al. Mol Cell. 2024 Feb 15;84(4):659-674.e7. doi: 10.1016/j.molcel.2023.12.039. Epub 2024 Jan 23. Mol Cell. 2024. PMID: 38266640 Free article.
EXO1 deficiency generates poly(ADP-ribose)-decorated DNA lesions during S phase that associate with unresolved DSBs and genomic instability in BRCA1-deficient but not in wild-type or BRCA2-deficient cells. Our data indicate that BRCA1/EXO1 double-deficient cells accumulate …
EXO1 deficiency generates poly(ADP-ribose)-decorated DNA lesions during S phase that associate with unresolved DSBs and genomic instability …
583 results