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Showing results for S. N. zharkovsky
Your search for S. N. Kharkovsky retrieved no results
CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages.
Yan L, Li Y, Fan F, Gou M, Xuan F, Feng W, Chithanathan K, Li W, Huang J, Li H, Chen W, Tian B, Wang Z, Tan S, Zharkovsky A, Hong LE, Tan Y, Tian L. Yan L, et al. BMC Med. 2023 Aug 4;21(1):286. doi: 10.1186/s12916-023-02959-8. BMC Med. 2023. PMID: 37542262 Free PMC article.
METHODS: We recruited a cohort of first episode schizophrenia (FES) patients (n = 51) and age- and sex-paired healthy controls (HCs) (n = 46) with evaluated stress perception. ...Furthermore, we studied a mouse model of chronic unpredictable stress (CUS) combined wi …
METHODS: We recruited a cohort of first episode schizophrenia (FES) patients (n = 51) and age- and sex-paired healthy controls (HCs) …
Gene-chemical interactions in the developing mammalian nervous system: Effects on proliferation, neurogenesis and differentiation.
Fox DA, Opanashuk L, Zharkovsky A, Weiss B. Fox DA, et al. Neurotoxicology. 2010 Sep;31(5):589-97. doi: 10.1016/j.neuro.2010.03.007. Epub 2010 Apr 8. Neurotoxicology. 2010. PMID: 20381523 Free PMC article.
Lisa Opanashuk discussed how dioxin [TCDD] binding to the arylhydrocarbon receptor [AhR], a transcription factor that regulates xenobiotic metabolizing enzymes and growth factors, increased granule cell formation and apoptosis in the developing mouse cerebellum. Alex Zharkovsk
Lisa Opanashuk discussed how dioxin [TCDD] binding to the arylhydrocarbon receptor [AhR], a transcription factor that regulates xenobiotic m …
Glial receptor PLXNB2 regulates schizophrenia-related stress perception via the amygdala.
Xuan FL, Yan L, Li Y, Fan F, Deng H, Gou M, Chithanathan K, Heinla I, Yuan L, Seppa K, Zharkovsky A, Kalda A, Hong LE, Hu GF, Tan Y, Tian L. Xuan FL, et al. Front Immunol. 2022 Oct 17;13:1005067. doi: 10.3389/fimmu.2022.1005067. eCollection 2022. Front Immunol. 2022. PMID: 36325348 Free PMC article.
Patients of first-episode schizophrenia (FES) with high stress (FES-hs, n=51) and low stress (FES-ls, n=50) perception and healthy controls (HCs) (n=49) were first recruited for neuroimaging and blood bulk RNA sequencing (RNA-seq). ...
Patients of first-episode schizophrenia (FES) with high stress (FES-hs, n=51) and low stress (FES-ls, n=50) perception and hea …
Schizophrenia-like phenotype of polysialyltransferase ST8SIA2-deficient mice.
Kröcher T, Malinovskaja K, Jürgenson M, Aonurm-Helm A, Zharkovskaya T, Kalda A, Röckle I, Schiff M, Weinhold B, Gerardy-Schahn R, Hildebrandt H, Zharkovsky A. Kröcher T, et al. Brain Struct Funct. 2015 Jan;220(1):71-83. doi: 10.1007/s00429-013-0638-z. Epub 2013 Sep 22. Brain Struct Funct. 2015. PMID: 24057454
A role of PSA-NCAM in the survival of retinal ganglion cells (RGCs) after kainic acid damage.
Lobanovskaya N, Zharkovsky A. Lobanovskaya N, et al. Neurotoxicology. 2019 May;72:101-106. doi: 10.1016/j.neuro.2019.02.009. Epub 2019 Feb 14. Neurotoxicology. 2019. PMID: 30772382
RGCs were visualized using an anti-Brn3a antibody. Endoneuraminidase N (NA) was administrated intravitreally to cleave PSA chains from NCAM. ...
RGCs were visualized using an anti-Brn3a antibody. Endoneuraminidase N (NA) was administrated intravitreally to cleave PSA chains fro …
PSA modification of NCAM supports the survival of injured retinal ganglion cells in adulthood.
Lobanovskaya N, Zharkovsky T, Jaako K, Jürgenson M, Aonurm-Helm A, Zharkovsky A. Lobanovskaya N, et al. Brain Res. 2015 Nov 2;1625:9-17. doi: 10.1016/j.brainres.2015.08.008. Epub 2015 Aug 28. Brain Res. 2015. PMID: 26319680
The aim of this study was to investigate whether PSA-NCAM promotes retinal ganglion cell (RGC) survival in transgenic mice with deficiencies in sialyltransferases or NCAM or after the administration of endoneuraminidase (Endo-N). RGC injury was induced by intravitreal admi …
The aim of this study was to investigate whether PSA-NCAM promotes retinal ganglion cell (RGC) survival in transgenic mice with deficiencies …
Nitric oxide synthesis inhibition attenuates morphine-induced place preference.
Kivastik T, Rutkauskaite J, Zharkovsky A. Kivastik T, et al. Pharmacol Biochem Behav. 1996 Apr;53(4):1013-5. doi: 10.1016/0091-3057(95)02092-6. Pharmacol Biochem Behav. 1996. PMID: 8801572
The aim of the present study was to investigate the role of NO in the mechanisms mediating the rewarding effects of morphine. Therefore, the influence of NO synthase inhibitor L-N-nitroarginine (L-NOARG) on morphine-induced place preference in rats was studied. ...
The aim of the present study was to investigate the role of NO in the mechanisms mediating the rewarding effects of morphine. Therefore, the …
The effects of glutamate receptor antagonists on cerebellar granule cell survival and development.
Klimaviciusa L, Safiulina D, Kaasik A, Klusa V, Zharkovsky A. Klimaviciusa L, et al. Neurotoxicology. 2008 Jan;29(1):101-8. doi: 10.1016/j.neuro.2007.09.006. Epub 2007 Sep 29. Neurotoxicology. 2008. PMID: 17981335
N-Methyl-d-aspartate (NMDA) receptor stimulation promotes neuronal survival and differentiation under both in vitro and in vivo conditions. ...
N-Methyl-d-aspartate (NMDA) receptor stimulation promotes neuronal survival and differentiation under both in vitro and in vivo condi
Dehydroepiandrosterone sulphate prevents oxygen-glucose deprivation-induced injury in cerebellar granule cell culture.
Kaasik A, Kalda A, Jaako K, Zharkovsky A. Kaasik A, et al. Neuroscience. 2001;102(2):427-32. doi: 10.1016/s0306-4522(00)00489-9. Neuroscience. 2001. PMID: 11166128
Furthermore, partial neuroprotection of dehydroepiandrosterone sulphate was also found against 1-methyl-4-phenylpyridinium, colchicine, glutamate and N-methyl-D-aspartate-induced toxicity. Further analysis demonstrated that dehydroepiandrosterone sulphate eliminated the ap …
Furthermore, partial neuroprotection of dehydroepiandrosterone sulphate was also found against 1-methyl-4-phenylpyridinium, colchicine, glut …
14 results