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Combined MEK/PD-L1 Inhibition Alters Peripheral Cytokines and Lymphocyte Populations Correlating with Improved Clinical Outcomes in Advanced Biliary Tract Cancer.
Ruggieri AN, Yarchoan M, Goyal S, Liu Y, Sharon E, Chen HX, Olson BM, Paulos CM, El-Rayes BF, Maithel SK, Azad NS, Lesinski GB. Ruggieri AN, et al. Clin Cancer Res. 2022 Oct 3;28(19):4336-4345. doi: 10.1158/1078-0432.CCR-22-1123. Clin Cancer Res. 2022. PMID: 35833954 Free PMC article. Clinical Trial.
National Cancer Institute (NCI) state of the science: Targeted radiosensitizers in colorectal cancer.
George TJ, Franke AJ, Chakravarthy AB, Das P, Dasari A, El-Rayes BF, Hong TS, Kinsella TJ, Landry JC, Lee JJ, Monjazeb AM, Jacobs SA, Raben D, Rahma OE, Williams TM, Wu C, Coleman CN, Vikram B, Ahmed MM. George TJ, et al. Cancer. 2019 Aug 15;125(16):2732-2746. doi: 10.1002/cncr.32150. Epub 2019 Apr 24. Cancer. 2019. PMID: 31017664 Free PMC article. Review.
Herein, the authors highlight the available evidence from preclinical models and early-phase studies, with an emphasis on promising developmental therapeutics undergoing prospective validation in larger scale clinical trials. This review by the National Cancer Institute's …
Herein, the authors highlight the available evidence from preclinical models and early-phase studies, with an emphasis on promising developm …
Clinical outcomes of advanced stage cancer patients treated with sequential immunotherapy in phase 1 clinical trials.
Martini DJ, Liu Y, Shabto JM, Lewis C, Kline MR, Collins H, Akce M, Kissick HT, Carthon BC, Shaib WL, Alese OB, Pillai RN, Steuer CE, Wu CS, Lawson DH, Kudchadkar RR, Master VA, El-Rayes BF, Ramalingam SS, Owonikoko TK, Harvey RD, Bilen MA. Martini DJ, et al. Invest New Drugs. 2019 Dec;37(6):1198-1206. doi: 10.1007/s10637-019-00736-0. Epub 2019 Feb 6. Invest New Drugs. 2019. PMID: 30725388 Free PMC article. Clinical Trial.