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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 2
1979 1
1980 2
1981 1
1982 1
1983 1
1990 1
1991 1
1992 2
1993 1
1996 3
1998 1
1999 3
2000 8
2001 4
2002 4
2003 13
2004 11
2005 11
2006 14
2007 12
2008 14
2009 14
2010 9
2011 15
2012 12
2013 16
2014 16
2015 15
2016 9
2017 8
2018 10
2019 3
2020 13
2021 10
2022 8
2023 12
2024 4

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259 results

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Page 1
Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex.
Strickson S, Houslay KF, Negri VA, Ohne Y, Ottosson T, Dodd RB, Huntington CC, Baker T, Li J, Stephenson KE, O'Connor AJ, Sagawe JS, Killick H, Moore T, Rees DG, Koch S, Sanden C, Wang Y, Gubbins E, Ghaedi M, Kolbeck R, Saumyaa S, Erjefält JS, Sims GP, Humbles AA, Scott IC, Romero Ros X, Cohen ES. Strickson S, et al. Eur Respir J. 2023 Sep 28;62(3):2202210. doi: 10.1183/13993003.02210-2022. Print 2023 Sep. Eur Respir J. 2023. PMID: 37442582 Free PMC article.
Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins.
Croucher NJ, Page AJ, Connor TR, Delaney AJ, Keane JA, Bentley SD, Parkhill J, Harris SR. Croucher NJ, et al. Nucleic Acids Res. 2015 Feb 18;43(3):e15. doi: 10.1093/nar/gku1196. Epub 2014 Nov 20. Nucleic Acids Res. 2015. PMID: 25414349 Free PMC article.
Simulations demonstrate the algorithm generates highly accurate reconstructions under realistically parameterized models of bacterial evolution, and achieves convergence in only a few hours on alignments of hundreds of bacterial genome sequences. Gubbins is appropriate for …
Simulations demonstrate the algorithm generates highly accurate reconstructions under realistically parameterized models of bacterial evolut …
A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa.
Lo SW, Gladstone RA, van Tonder AJ, Du Plessis M, Cornick JE, Hawkins PA, Madhi SA, Nzenze SA, Kandasamy R, Ravikumar KL, Elmdaghri N, Kwambana-Adams B, Almeida SCG, Skoczynska A, Egorova E, Titov L, Saha SK, Paragi M, Everett DB, Antonio M, Klugman KP, Li Y, Metcalf BJ, Beall B, McGee L, Breiman RF, Bentley SD, von Gottberg A; Global Pneumococcal Sequencing Consortium. Lo SW, et al. J Antimicrob Chemother. 2020 Mar 1;75(3):512-520. doi: 10.1093/jac/dkz477. J Antimicrob Chemother. 2020. PMID: 31789384 Free PMC article.
RESULTS: We identified tet(S/M) in 131 pneumococcal isolates and none carried other known tet genes. ...All but two tet(S/M)-positive isolates belonged to clonal complex (CC) 230. A global phylogeny of CC230 (n=389) revealed that tet(S/M)-positive isolates fo …
RESULTS: We identified tet(S/M) in 131 pneumococcal isolates and none carried other known tet genes. ...All but two tet(S/M)-p …
Genomic characterisation of multidrug-resistant Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii in two intensive care units in Hanoi, Viet Nam: a prospective observational cohort study.
Roberts LW, Hoi LT, Khokhar FA, Hoa NT, Giang TV, Bui C, Ninh TH, Co DX, Binh NG, Long HB, Huong DT, Bryan JE, Herrick A, Feltwell T, Nadjm B, van Doorn HR, Parkhill J, Trung NV, Kinh NV, Iqbal Z, Török ME. Roberts LW, et al. Lancet Microbe. 2022 Nov;3(11):e857-e866. doi: 10.1016/S2666-5247(22)00181-1. Epub 2022 Oct 4. Lancet Microbe. 2022. PMID: 36206776 Free article.
Phylogenies based on the de-novo assemblies (SPAdes) were constructed with MAFFT (PARsnp), Gubbins, and RAxML. Resistance genes were detected with Abricate against the US National Center for Biotechnology Information database. ...
Phylogenies based on the de-novo assemblies (SPAdes) were constructed with MAFFT (PARsnp), Gubbins, and RAxML. Resistance genes were …
Veterinary and human vaccine evaluation methods.
Knight-Jones TJ, Edmond K, Gubbins S, Paton DJ. Knight-Jones TJ, et al. Proc Biol Sci. 2014 Apr 16;281(1784):20132839. doi: 10.1098/rspb.2013.2839. Print 2014 Jun 7. Proc Biol Sci. 2014. PMID: 24741009 Free PMC article. Review.
Semisynthesis of A6-A11 lactam insulin.
Xu R, Jap E, Gubbins B, Hagemeyer CE, Karas JA. Xu R, et al. J Pept Sci. 2024 Feb;30(2):e3542. doi: 10.1002/psc.3542. Epub 2023 Sep 11. J Pept Sci. 2024. PMID: 37697741 Free PMC article.
A key consideration during analogue development is formulation stability, which can be improved via the replacement of insulin's A6-A11 disulfide bond with stable mimetics. Unfortunately, analogues such as these require extensive chemical synthesis to incorporate the nonna …
A key consideration during analogue development is formulation stability, which can be improved via the replacement of insulin's A6-A …
Clinical and molecular characteristics of carbapenem non-susceptible Escherichia coli: A nationwide survey from Oman.
Al-Farsi HM, Camporeale A, Ininbergs K, Al-Azri S, Al-Muharrmi Z, Al-Jardani A, Giske CG. Al-Farsi HM, et al. PLoS One. 2020 Oct 9;15(10):e0239924. doi: 10.1371/journal.pone.0239924. eCollection 2020. PLoS One. 2020. PMID: 33036018 Free PMC article.
Maxiuium likelihood SNP-tree was performed by RAxML after variant calling and removal of recombination regions with Snippy and Gubbins, respectively. Resistance genes, plasmid replicon types, virulence genes, and prophage were also characterised. ...
Maxiuium likelihood SNP-tree was performed by RAxML after variant calling and removal of recombination regions with Snippy and Gubbins …
Diversity of carbapenem-resistant Acinetobacter baumannii and bacteriophage-mediated spread of the Oxa23 carbapenemase.
Abouelfetouh A, Mattock J, Turner D, Li E, Evans BA. Abouelfetouh A, et al. Microb Genom. 2022 Feb;8(2):000752. doi: 10.1099/mgen.0.000752. Microb Genom. 2022. PMID: 35104206 Free PMC article.
The core-gene compliment was determined using Roary, and analyses of recombination were performed in Gubbins. Multilocus sequence typing (MLST) sequence type (ST) and antibiotic-resistance genes were identified. ...
The core-gene compliment was determined using Roary, and analyses of recombination were performed in Gubbins. Multilocus sequence typ …
259 results