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Page 1
Causal risk and protective factors in rheumatoid arthritis: A genetic update.
Arleevskaya M, Takha E, Petrov S, Kazarian G, Novikov A, Larionova R, Valeeva A, Shuralev E, Mukminov M, Bost C, Renaudineau Y. Arleevskaya M, et al. J Transl Autoimmun. 2021 Sep 3;4:100119. doi: 10.1016/j.jtauto.2021.100119. eCollection 2021. J Transl Autoimmun. 2021. PMID: 34522877 Free PMC article.
Finally, factors can be also classified according to their direct capacity to interfere with the IL-6/CRP/sIL-IL6R proinflammatory pathway as risk factor (body fat, cardiometabolic factors, type 2 diabetes, depressive syndrome) or either as protective factors by controlling of sI …
Finally, factors can be also classified according to their direct capacity to interfere with the IL-6/CRP/sIL-IL6R proinflammatory pathway a …
Alzheimer's disease Advax(CpG)- adjuvanted MultiTEP-based dual and single vaccines induce high-titer antibodies against various forms of tau and Abeta pathological molecules.
Davtyan H, Zagorski K, Rajapaksha H, Hovakimyan A, Davtyan A, Petrushina I, Kazarian K, Cribbs DH, Petrovsky N, Agadjanyan MG, Ghochikyan A. Davtyan H, et al. Sci Rep. 2016 Jul 1;6:28912. doi: 10.1038/srep28912. Sci Rep. 2016. PMID: 27363809 Free PMC article.
Although beta-amyloid (Abeta) may be the primary driver of Alzheimer's disease (AD) pathology, accumulation of pathological tau correlates with dementia in AD patients. Thus, the prevention/inhibition of AD may require vaccine/s targeting Abeta and tau simultaneousl …
Although beta-amyloid (Abeta) may be the primary driver of Alzheimer's disease (AD) pathology, accumulation of pathological tau corre …
Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency.
Agadjanyan MG, Zagorski K, Petrushina I, Davtyan H, Kazarian K, Antonenko M, Davis J, Bon C, Blurton-Jones M, Cribbs DH, Ghochikyan A. Agadjanyan MG, et al. Mol Neurodegener. 2017 May 5;12(1):33. doi: 10.1186/s13024-017-0172-1. Mol Neurodegener. 2017. PMID: 28472993 Free PMC article.
Importantly, Armanezumab (i) bound to tau with high affinity as determined by Biacore; (ii) bound pathological tau in brains from AD, FTD and Pick's disease cases; (iii) inhibited seeding effect of aggregated tau from brain lysate of P301S Tg mice; (iv) inhibited cytotoxic …
Importantly, Armanezumab (i) bound to tau with high affinity as determined by Biacore; (ii) bound pathological tau in brains from AD, FTD an …
Atherosclerotic aortic gangliosides enhance integrin-mediated platelet adhesion to collagen.
Wen FQ, Jabbar AA, Patel DA, Kazarian T, Valentino LA. Wen FQ, et al. Arterioscler Thromb Vasc Biol. 1999 Mar;19(3):519-24. doi: 10.1161/01.atv.19.3.519. Arterioscler Thromb Vasc Biol. 1999. PMID: 10073952
Samples of aortic tissue taken from areas involved with atherosclerotic plaque demonstrated accumulation of gangliosides (64.9+/-6.5 nmol/g wet weight) compared with gangliosides isolated from control normal aortic tissue taken from children who died of noncardiac causes ( …
Samples of aortic tissue taken from areas involved with atherosclerotic plaque demonstrated accumulation of gangliosides (64.9+/-6.5 nmol/ …
Development of a novel fluorescent tag O-2-[aminoethyl]fluorescein for the electrophoretic separation of oligosaccharides.
Kazarian AA, Smith JA, Hilder EF, Breadmore MC, Quirino JP, Suttil J. Kazarian AA, et al. Anal Chim Acta. 2010 Mar 10;662(2):206-13. doi: 10.1016/j.aca.2010.01.011. Epub 2010 Jan 18. Anal Chim Acta. 2010. PMID: 20171321
The tag was synthesised using three consecutive steps namely: esterification, alkylation and hydrolysis, specifically designed to offer a flexible way in which to make an assortment of fluorescent tags from cheap and readily available starting reagents (typically less than $1 per …
The tag was synthesised using three consecutive steps namely: esterification, alkylation and hydrolysis, specifically designed to offer a fl …
Chemical imaging of live cancer cells in the natural aqueous environment.
Kuimova MK, Chan KL, Kazarian SG. Kuimova MK, et al. Appl Spectrosc. 2009 Feb;63(2):164-71. doi: 10.1366/000370209787391969. Appl Spectrosc. 2009. PMID: 19215645 Free article.
Using both approaches, the ATR-FT-IR spectroscopic signatures allow the differentiation between several cellular organelles, e.g., the nucleus and the endoplasmic reticulum (ER). The overall cell shape can be defined by the distribution of the amide II band in the measured …
Using both approaches, the ATR-FT-IR spectroscopic signatures allow the differentiation between several cellular organelles, e.g., th …
Combined approach of FTIR imaging and conventional dissolution tests applied to drug release.
van der Weerd J, Kazarian SG. van der Weerd J, et al. J Control Release. 2004 Aug 11;98(2):295-305. doi: 10.1016/j.jconrel.2004.05.007. J Control Release. 2004. PMID: 15262420
FTIR imaging in attenuated total reflection (ATR) mode allows simultaneous measurements of the distribution of different components in the tablet, e.g., drug, polymer and water as a function of time. These imaging measurements were carried out in a combined compaction and …
FTIR imaging in attenuated total reflection (ATR) mode allows simultaneous measurements of the distribution of different components in the t …
[The gas chromatographic determination of dichlorobutenes and trichlorobutenes in washings from the skin].
Kazarian KO. Kazarian KO. Gig Tr Prof Zabol. 1992;(7):32-4. Gig Tr Prof Zabol. 1992. PMID: 1296913 Russian.
A sensitive selective method of unsaturated chlorated hydrocarbons detection by means of gas chromatography in skin was worked out. The limits are: for 3,4-dichlorobutene (DCB)-1-0.0024 mu g, for 1,3 DCB-2-0.0027 mu g, for 1,4-DCB-2 (cys)-0.0024 mu g, for 1,4 …
A sensitive selective method of unsaturated chlorated hydrocarbons detection by means of gas chromatography in skin was worked out. The limi …
[Defects in conducting case histories in urgent abdominal surgery and their importance].
Iarema IV, Pashinian GA, Kazarian VM, Kim PP. Iarema IV, et al. Vestn Khir Im I I Grek. 2006;165(3):86-8. Vestn Khir Im I I Grek. 2006. PMID: 16881187 Russian.
Information available in case histories is of great importance, e.g. for court examinations on "medical suits". So, we have investigated 472 case histories for the period from 2000 through 2004. ...High professional and juridical competence is thought to be the way to avoi …
Information available in case histories is of great importance, e.g. for court examinations on "medical suits". So, we have investiga …
11 results