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Therapeutic approaches to target alpha-synuclein pathology.
Brundin P, Dave KD, Kordower JH. Brundin P, et al. Exp Neurol. 2017 Dec;298(Pt B):225-235. doi: 10.1016/j.expneurol.2017.10.003. Epub 2017 Oct 4. Exp Neurol. 2017. PMID: 28987463 Free PMC article. Review.
COVID-19 thromboembolism incidence, risk factors, and anticoagulation practices from a Chicago metropolitan US population.
Berg S, Kim SH, Wozniak A, Odetola O, Arain S, Aleem A, Coggan J, Dave A, Elliott E, Guerrettaz R, Dalal H, Lee R, Kodali A, Moore P, Patel S, Rajakumar P, Qin S, Delgado Ramos G, Schwartz C, Esmail F, Feltman Frank R, Murchie E, Pax L, Yun N, Zhang Y, Barton K, Hagen P, Hossain N, Larson ML, Mai H, Nand S, Phelan K, Venugopal P, Stiff P, Saraf S. Berg S, et al. Am J Hematol. 2022 Jun 1;97(6):E217-E220. doi: 10.1002/ajh.26541. Epub 2022 Mar 28. Am J Hematol. 2022. PMID: 35303373 Free article. No abstract available.
Structural racism is a mediator of disparities in acute myeloid leukemia outcomes.
Abraham IE, Rauscher GH, Patel AA, Pearse WB, Rajakumar P, Burkart M, Aleem A, Dave A, Bharadwaj S, Paydary K, Acevedo-Mendez M, Goparaju K, Gomez R, Carlson K, Tsai SB, Quigley JG, Galvin JP, Zia M, Larson ML, Berg S, Stock W, Altman JK, Khan I. Abraham IE, et al. Blood. 2022 Apr 7;139(14):2212-2226. doi: 10.1182/blood.2021012830. Blood. 2022. PMID: 35061876 Free PMC article.
Cornelia de Lange syndrome in diverse populations.
Dowsett L, Porras AR, Kruszka P, Davis B, Hu T, Honey E, Badoe E, Thong MK, Leon E, Girisha KM, Shukla A, Nayak SS, Shotelersuk V, Megarbane A, Phadke S, Sirisena ND, Dissanayake VHW, Ferreira CR, Kisling MS, Tanpaiboon P, Uwineza A, Mutesa L, Tekendo-Ngongang C, Wonkam A, Fieggen K, Batista LC, Moretti-Ferreira D, Stevenson RE, Prijoles EJ, Everman D, Clarkson K, Worthington J, Kimonis V, Hisama F, Crowe C, Wong P, Johnson K, Clark RD, Bird L, Masser-Frye D, McDonald M, Willems P, Roeder E, Saitta S, Anyane-Yeoba K, Demmer L, Hamajima N, Stark Z, Gillies G, Hudgins L, Dave U, Shalev S, Siu V, Ades A, Dubbs H, Raible S, Kaur M, Salzano E, Jackson L, Deardorff M, Kline A, Summar M, Muenke M, Linguraru MG, Krantz ID. Dowsett L, et al. Am J Med Genet A. 2019 Feb;179(2):150-158. doi: 10.1002/ajmg.a.61033. Epub 2019 Jan 6. Am J Med Genet A. 2019. PMID: 30614194 Free PMC article.
Genetic diversity is a predictor of mortality in humans.
Bihlmeyer NA, Brody JA, Smith AV, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza SS, Teumer A, Coresh J, Pankow JS, Franceschini N, Scaria A, Oshima J, Psaty BM, Gudnason V, Eiriksdottir G, Harris TB, Li H, Karasik D, Kiel DP, Garcia M, Liu Y, Faul JD, Kardia SL, Zhao W, Ferrucci L, Allerhand M, Liewald DC, Redmond P, Starr JM, De Jager PL, Evans DA, Direk N, Ikram MA, Uitterlinden A, Homuth G, Lorbeer R, Grabe HJ, Launer L, Murabito JM, Singleton AB, Weir DR, Bandinelli S, Deary IJ, Bennett DA, Tiemeier H, Kocher T, Lumley T, Arking DE. Bihlmeyer NA, et al. BMC Genet. 2014 Dec 29;15:159. doi: 10.1186/s12863-014-0159-7. BMC Genet. 2014. PMID: 25543667 Free PMC article.
Persistent leukocytosis in polycythemia vera is associated with disease evolution but not thrombosis.
Ronner L, Podoltsev N, Gotlib J, Heaney ML, Kuykendall AT, O'Connell C, Shammo J, Fleischman AG, Scherber RM, Mesa R, Yacoub A, Perkins C, Meckstroth S, Behlman L, Chiaramonte M, Salehi M, Ziadkhanpour K, Nguyen H, Siwoski O, Hung AK, Janania Martinez M, Nguyen J, Patel S, Kollipara R, Dave A, Randall M, Grant M, Harrison M, Fernandez Soto P, Tremblay D, Hoffman R, Moshier E, Mascarenhas J. Ronner L, et al. Blood. 2020 May 7;135(19):1696-1703. doi: 10.1182/blood.2019003347. Blood. 2020. PMID: 32107559 Free PMC article.
Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4).
Beach TG, Serrano GE, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbillé AG, Letournel F, Munoz DG, White CL 3rd, Schneider J, Crary JF, Sue LI, Adler CH, Glass MJ, Intorcia AJ, Walker JE, Foroud T, Coffey CS, Ecklund D, Riss H, Goßmann J, König F, Kopil CM, Arnedo V, Riley L, Linder C, Dave KD, Jennings D, Seibyl J, Mollenhauer B, Chahine L; Systemic Synuclein Sampling Study (S4). Beach TG, et al. J Neuropathol Exp Neurol. 2018 Sep 1;77(9):793-802. doi: 10.1093/jnen/nly056. J Neuropathol Exp Neurol. 2018. PMID: 30107604 Free PMC article.
Methamphetamine decreases K+ channel function in human fetal astrocytes by activating the trace amine-associated receptor type-1.
Dave S, Chen L, Yu C, Seaton M, Khodr CE, Al-Harthi L, Hu XT. Dave S, et al. J Neurochem. 2019 Jan;148(1):29-45. doi: 10.1111/jnc.14606. Epub 2018 Nov 19. J Neurochem. 2019. PMID: 30295919 Free PMC article.
These changes were associated with a decreased time constant (T), and mimicked by blocking the two-pore domain K(+) (K(2P) )/K(2P) -like and K(v) /K(v) -like channels, respectively. ...
These changes were associated with a decreased time constant (T), and mimicked by blocking the two-pore domain K(+) (K(2P) )/K(2P) -l …
Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema.
Jampol LM, Glassman AR, Liu D, Aiello LP, Bressler NM, Duh EJ, Quaggin S, Wells JA, Wykoff CC; Diabetic Retinopathy Clinical Research Network. Jampol LM, et al. Ophthalmology. 2018 Jul;125(7):1054-1063. doi: 10.1016/j.ophtha.2018.01.019. Epub 2018 Mar 7. Ophthalmology. 2018. PMID: 29525602 Free PMC article. Clinical Trial.