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Showing results for running zhu
Your search for Ruoning Zhu retrieved no results
Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice.
Zhang SS, Zhu L, Peng Y, Zhang L, Chao FL, Jiang L, Xiao Q, Liang X, Tang J, Yang H, He Q, Guo YJ, Zhou CN, Tang Y. Zhang SS, et al. J Neuroinflammation. 2022 Feb 5;19(1):34. doi: 10.1186/s12974-022-02401-5. J Neuroinflammation. 2022. PMID: 35123512 Free PMC article.
Running mice had free access to a running wheel for 3 months. Behavioral tests, [18]F-FDG-PET and hippocampal RNA-Seq were performed. ...The level of sTREM2 decreased in the plasma of APP/PS1 running mice. The number of microglia, the length and endpoints of …
Running mice had free access to a running wheel for 3 months. Behavioral tests, [18]F-FDG-PET and hippocampal RNA-Seq were per …
Nrf2 epigenetic derepression induced by running exercise protects against osteoporosis.
Chen X, Zhu X, Wei A, Chen F, Gao Q, Lu K, Jiang Q, Cao W. Chen X, et al. Bone Res. 2021 Feb 26;9(1):15. doi: 10.1038/s41413-020-00128-8. Bone Res. 2021. PMID: 33637693 Free PMC article.
Here, we report that epigenetic derepression of nuclear factor erythroid derived 2-related factor-2 (Nrf2), a master regulator of oxidative stress critically involved in the pathogenesis of OP, mediates the significant osteoprotective effects of running exercise (RE) in a …
Here, we report that epigenetic derepression of nuclear factor erythroid derived 2-related factor-2 (Nrf2), a master regulator of oxidative …
Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction.
Zhou Q, Deng J, Yao J, Song J, Meng D, Zhu Y, Xu M, Liang Y, Xu J, Sluijter JP, Xiao J. Zhou Q, et al. EBioMedicine. 2021 Dec;74:103713. doi: 10.1016/j.ebiom.2021.103713. Epub 2021 Nov 24. EBioMedicine. 2021. PMID: 34837851 Free PMC article.
METHODS: HIPK2(-/-) mice and miR-222(-/-) rats, HIPK2 inhibitor (PKI1H) and adeno-associated virus serotype 9 (AAV9) carrying miR-222 were applied in the study. Animals were subjected to running, swimming, acute MI or post-MI remodeling. HIPK2 inhibition and P53 activator …
METHODS: HIPK2(-/-) mice and miR-222(-/-) rats, HIPK2 inhibitor (PKI1H) and adeno-associated virus serotype 9 (AAV9) carrying miR-222 were a …
Long-term voluntary exercise inhibited AGE/RAGE and microglial activation and reduced the loss of dendritic spines in the hippocampi of APP/PS1 transgenic mice.
Wang YY, Zhou YN, Jiang L, Wang S, Zhu L, Zhang SS, Yang H, He Q, Liu L, Xie YH, Liang X, Tang J, Chao FL, Tang Y. Wang YY, et al. Exp Neurol. 2023 May;363:114371. doi: 10.1016/j.expneurol.2023.114371. Epub 2023 Mar 4. Exp Neurol. 2023. PMID: 36871860
Alzheimer's disease (AD) is closely related to hippocampal synapse loss, which can be alleviated by running exercise. However, further studies are needed to determine whether running exercise reduces synapse loss in the hippocampus in an AD model by regulating micro …
Alzheimer's disease (AD) is closely related to hippocampal synapse loss, which can be alleviated by running exercise. However, furthe …
The effects of voluntary running exercise on the astrocytes of the medial prefrontal cortex in APP/PS1 mice.
Liu M, Zhu L, Guo YJ, Zhang SS, Jiang L, Zhang Y, Chao FL, Tang Y. Liu M, et al. J Comp Neurol. 2023 Aug;531(11):1147-1162. doi: 10.1002/cne.25485. Epub 2023 May 5. J Comp Neurol. 2023. PMID: 37146123
Pathological changes in the medial prefrontal cortex (mPFC) and astrocytes are closely associated with Alzheimer's disease (AD). Voluntary running has been found to effectively delay AD. However, the effects of voluntary running on mPFC astrocytes in AD are unclear. …
Pathological changes in the medial prefrontal cortex (mPFC) and astrocytes are closely associated with Alzheimer's disease (AD). Voluntary …
3-Ethyl-1H-1,2,4-triazole-5(4H)-thione.
Jing B, Du YC, Zhu AX. Jing B, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):o1802. doi: 10.1107/S1600536812021927. Epub 2012 May 19. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22719575 Free PMC article.
In the crystal, adjacent mol-ecules are linked by N-HN and N-HS hydrogen bonds into chains running along the a axis. pi-pi stacking inter-actions between the triazole rings [centroid-centroid distance = 3.740 (1) A and inter-planar distance = 3.376 A] may further stabilize …
In the crystal, adjacent mol-ecules are linked by N-HN and N-HS hydrogen bonds into chains running along the a axis. pi-pi stacking i …
MnBa(2)(HPO(4))(2)(H(2)PO(4))(2).
Sun W, Sun LZ, Zhu TT, Zhao BC, Mi JX. Sun W, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):i49. doi: 10.1107/S1600536812022775. Epub 2012 May 26. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22719278 Free PMC article.
The structure is built up of an infinite {[Mn(HPO(4))(2)(H(2)PO(4))(2)](4-)}(n) chain running along [100], which consists of alternate MnO(6) octa-hedra and [PO(4)] tetra-hedra, in which the centrosymmetric MnO(6) octa-hedra share their four equatorial O-atom corners with …
The structure is built up of an infinite {[Mn(HPO(4))(2)(H(2)PO(4))(2)](4-)}(n) chain running along [100], which consists of alternat …
A Novel Microcontroller-Based System for the Wheel-Running Activity in Mice.
Zhu M, Kasaragod DK, Kikutani K, Taguchi K, Aizawa H. Zhu M, et al. eNeuro. 2021 Nov 22;8(6):ENEURO.0260-21.2021. doi: 10.1523/ENEURO.0260-21.2021. Print 2021 Nov-Dec. eNeuro. 2021. PMID: 34479979 Free PMC article.
Voluntary wheel-running activity is a way to assess rodents' circadian rhythm and motivation for exercise. ...With the WRAQ, we can record the wheel-running activity and illumination data for at least 30 d. Applying the WRAQ to an endotoxemia mouse model robustly de …
Voluntary wheel-running activity is a way to assess rodents' circadian rhythm and motivation for exercise. ...With the WRAQ, we can r …
Running exercise alleviates hippocampal neuroinflammation and shifts the balance of microglial M1/M2 polarization through adiponectin/AdipoR1 pathway activation in mice exposed to chronic unpredictable stress.
Liu L, Tang J, Liang X, Li Y, Zhu P, Zhou M, Qin L, Deng Y, Li J, Wang Y, Jiang L, Huang D, Zhou Y, Wang S, Xiao Q, Luo Y, Tang Y. Liu L, et al. Mol Psychiatry. 2024 Feb 15. doi: 10.1038/s41380-024-02464-1. Online ahead of print. Mol Psychiatry. 2024. PMID: 38361125
Running exercise has been shown to alleviate depressive symptoms. ...Running exercise increases circulating levels of adiponectin which is known to cross the blood-brain barrier and suppress inflammatory responses. ...
Running exercise has been shown to alleviate depressive symptoms. ...Running exercise increases circulating levels of adiponec …
Running exercise protects spinophilin-immunoreactive puncta and neurons in the medial prefrontal cortex of APP/PS1 transgenic mice.
Zhu L, Fan JH, Chao FL, Zhou CN, Jiang L, Zhang Y, Luo YM, Zhang L, Xiao Q, Yang H, Zhang SS, Wu H, Tang Y. Zhu L, et al. J Comp Neurol. 2022 Apr;530(6):858-870. doi: 10.1002/cne.25252. Epub 2021 Oct 20. J Comp Neurol. 2022. PMID: 34585379
In addition, running-induced improvements in spatial learning and memory were significantly associated with running-induced increases in spinophilin-immunoreactive puncta and neurons numbers in the mPFC. Running exercise could delay the loss of spinophilin-im …
In addition, running-induced improvements in spatial learning and memory were significantly associated with running-induced in …
592 results