Coadministration of CD19- and CD22-Directed Chimeric Antigen Receptor T-Cell Therapy in Childhood B-Cell Acute Lymphoblastic Leukemia: A Single-Arm, Multicenter, Phase II Trial.
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J Clin Oncol. 2023 Mar 20;41(9):1670-1683. doi: 10.1200/JCO.22.01214. Epub 2022 Nov 8.
J Clin Oncol. 2023.
PMID: 36346962
Free PMC article.
Clinical Trial.
PATIENTS AND METHODS: This phase II trial enrolled 225 evaluable patients age 20 years between September 17, 2019, and December 31, 2021. We first conducted a safety run-in stage to determine the recommended dose. After interim analysis of the first 30 patients treated (27 …
PATIENTS AND METHODS: This phase II trial enrolled 225 evaluable patients age 20 years between September 17, 2019, and December 31, 2021. We …