Factors Associated with Mortality with Tuberculosis Diagnosis in Indigenous Populations in Peru 2015-2019

Int J Environ Res Public Health. 2022 Nov 15;19(22):15019. doi: 10.3390/ijerph192215019.

Abstract

Objective: To identify factors associated with mortality in indigenous populations diagnosed with tuberculosis in Peru, 2015-2019.

Methods: We conducted a nested case-control study in a retrospective cohort using the registry of indigenous peoples of the National Health Strategy for TB Prevention and Control of the Ministry of Health of Peru. A descriptive analysis was performed, and then bivariate and multivariate logistic regression was used to evaluate associations between the variables and the outcome (alive-deceased). The results are shown as OR with their respective 95% confidence intervals.

Results: The mortality rate of the total indigenous population of Peru was 1.75 deaths per 100,000 indigenous people diagnosed with TB. The community of Kukama Kukamiria-Yagua reported 505 (28.48%) individuals, followed by the Shipibo-Konibo community with 385. The final logistic model showed that indigenous males (OR = 1.93; 95% CI: 1.001-3.7) with a history of HIV prior to TB (OR = 16.7; 95% CI: 4.7-58.7), and indigenous people in old age (OR = 2.95; 95% CI: 1.5-5.7) were factors associated with a greater chance of dying from TB.

Conclusions: It is important to reorient health services among indigenous populations, especially those related to improving a timely diagnosis and early treatment of TB/HIV co-infection, to ensure comprehensive care for this population considering that they are vulnerable groups.

Keywords: indigenous; logistic regression; mortality; tuberculosis.

MeSH terms

  • Case-Control Studies
  • HIV Infections* / epidemiology
  • Humans
  • Indigenous Peoples
  • Male
  • Peru / epidemiology
  • Retrospective Studies
  • Tuberculosis* / diagnosis
  • Tuberculosis* / epidemiology

Grants and funding

This research has not received specific support from public sector agencies, commercial sector, or non-profit entities.