Misinterpretation in virus clearance studies of biological products due to an uncommon discrepancy between cytopathic effects and infectivity of human immunodeficiency virus (HIV)

Biologicals. 2013 Mar;41(2):125-7. doi: 10.1016/j.biologicals.2012.10.004. Epub 2012 Nov 3.

Authors

Takeru Urayama, Roslyn Cameron, Tetsuo Sato, Mikihiro Yunoki, Kazuyoshi Ikuta

PMID: 23131459
DOI: 10.1016/j.biologicals.2012.10.004

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Biological Products / pharmacology*
CD4-Positive T-Lymphocytes / cytology
CD4-Positive T-Lymphocytes / drug effects*
CD4-Positive T-Lymphocytes / virology
Cell Line
Cell Survival / drug effects
Culture Media, Conditioned / metabolism
Culture Media, Conditioned / pharmacology
Cytopathogenic Effect, Viral / drug effects
Drug Evaluation, Preclinical / methods
Giant Cells / drug effects
HIV-1 / drug effects*
HIV-1 / metabolism
HIV-1 / physiology
Host-Pathogen Interactions / drug effects
Humans
Reproducibility of Results

Substances

Biological Products
Culture Media, Conditioned