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Page 1
Progenitor recruitment and adipogenic lipolysis contribute to the anabolic actions of parathyroid hormone on the skeleton.
FASEB J. 2019 Feb;33(2):2885-2898. doi: 10.1096/fj.201800948RR. Epub 2018 Oct 24.
FASEB J. 2019.
PMID: 30354669
Free PMC article.
Lipolysis supports bone formation by providing osteoblasts with endogenous fatty acid substrates to maintain bioenergetic status.
Nandy A, Helderman RCM, Thapa S, Jayapalan S, Richards A, Narayani N, Czech MP, Rosen CJ, Rendina-Ruedy E.
Nandy A, et al. Among authors: helderman rcm.
Bone Res. 2023 Nov 24;11(1):62. doi: 10.1038/s41413-023-00297-2.
Bone Res. 2023.
PMID: 38001111
Free PMC article.
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Untargeted metabolomics in primary murine bone marrow stromal cells reveals distinct profile throughout osteoblast differentiation.
Misra BB, Jayapalan S, Richards AK, Helderman RCM, Rendina-Ruedy E.
Misra BB, et al. Among authors: helderman rcm.
Metabolomics. 2021 Sep 18;17(10):86. doi: 10.1007/s11306-021-01829-9.
Metabolomics. 2021.
PMID: 34537901
Free PMC article.
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Loss of function of lysosomal acid lipase (LAL) profoundly impacts osteoblastogenesis and increases fracture risk in humans.
Helderman RC, Whitney DG, Duta-Mare M, Akhmetshina A, Vujic N, Jayapalan S, Nyman JS, Misra BB, Rosen CJ, Czech MP, Kratky D, Rendina-Ruedy E.
Helderman RC, et al.
Bone. 2021 Jul;148:115946. doi: 10.1016/j.bone.2021.115946. Epub 2021 Apr 7.
Bone. 2021.
PMID: 33838322
Free PMC article.
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Early reduced bone formation following burn injury in rats is not inversely related to marrow adiposity.
El Ayadi A, Helderman RC, Finnerty CC, Herndon DN, Rosen CJ, Klein GL.
El Ayadi A, et al. Among authors: helderman rc.
Osteoporos Sarcopenia. 2019 Sep;5(3):84-86. doi: 10.1016/j.afos.2019.08.001. Epub 2019 Aug 28.
Osteoporos Sarcopenia. 2019.
PMID: 31728425
Free PMC article.
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