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Page 1
Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico.
Dunkle LM, Kotloff KL, Gay CL, Áñez G, Adelglass JM, Barrat Hernández AQ, Harper WL, Duncanson DM, McArthur MA, Florescu DF, McClelland RS, Garcia-Fragoso V, Riesenberg RA, Musante DB, Fried DL, Safirstein BE, McKenzie M, Jeanfreau RJ, Kingsley JK, Henderson JA, Lane DC, Ruíz-Palacios GM, Corey L, Neuzil KM, Coombs RW, Greninger AL, Hutter J, Ake JA, Smith K, Woo W, Cho I, Glenn GM, Dubovsky F; 2019nCoV-301 Study Group. Dunkle LM, et al. N Engl J Med. 2022 Feb 10;386(6):531-543. doi: 10.1056/NEJMoa2116185. Epub 2021 Dec 15. N Engl J Med. 2022. PMID: 34910859 Free PMC article. Clinical Trial.
Over a period of 3 months, 77 cases of Covid-19 were noted - 14 among vaccine recipients and 63 among placebo recipients (vaccine efficacy, 90.4%; 95% confidence interval [CI], 82.9 to 94.6; P<0.001). Ten moderate and 4 severe cases occurred, all in placebo recipients, …
Over a period of 3 months, 77 cases of Covid-19 were noted - 14 among vaccine recipients and 63 among placebo recipients (vaccine efficacy, …
Intravitreal antisense oligonucleotide sepofarsen in Leber congenital amaurosis type 10: a phase 1b/2 trial.
Russell SR, Drack AV, Cideciyan AV, Jacobson SG, Leroy BP, Van Cauwenbergh C, Ho AC, Dumitrescu AV, Han IC, Martin M, Pfeifer WL, Sohn EH, Walshire J, Garafalo AV, Krishnan AK, Powers CA, Sumaroka A, Roman AJ, Vanhonsebrouck E, Jones E, Nerinckx F, De Zaeytijd J, Collin RWJ, Hoyng C, Adamson P, Cheetham ME, Schwartz MR, den Hollander W, Asmus F, Platenburg G, Rodman D, Girach A. Russell SR, et al. Nat Med. 2022 May;28(5):1014-1021. doi: 10.1038/s41591-022-01755-w. Epub 2022 Apr 4. Nat Med. 2022. PMID: 35379979 Free PMC article. Clinical Trial.
Six patients received sepofarsen 160 g/80 g, and five patients received sepofarsen 320 g/160 g. Ten of 11 (90.9%) patients developed ocular AEs in the treated eye (5/6 with 160 g/80 g; 5/5 with 320 g/160 g) versus one of 11 (9.1%) in the untreated eye; most were mild in se …
Six patients received sepofarsen 160 g/80 g, and five patients received sepofarsen 320 g/160 g. Ten of 11 (90.9%) patients developed …
Ten-year follow-up on efficacy, immunogenicity and safety of two doses of a combined measles-mumps-rubella-varicella vaccine or one dose of monovalent varicella vaccine: Results from five East European countries.
Prymula R, Povey M, Brzostek J, Cabrnochova H, Chlibek R, Czajka H, Leviniene G, Man S, Neamtu M, Pazdiora P, Plesca D, Ruzkova R, Stefkovicova M, Usonis V, Verdanova D, Wysocki J, Casabona G, Habib MA. Prymula R, et al. Vaccine. 2021 May 6;39(19):2643-2651. doi: 10.1016/j.vaccine.2021.03.085. Epub 2021 Apr 12. Vaccine. 2021. PMID: 33858718 Free article. Clinical Trial.
RESULTS: A total of 3705 children were vaccinated (1590, MMRV group; 1586, MMR + V group; 529, MMR group). There were 663 confirmed varicella cases (47, MMRV group; 349, MMR + V group; 267, MMR group). VE ranged between 95.4% (Lithuania) and 97.4% (Slovakia) in the …
RESULTS: A total of 3705 children were vaccinated (1590, MMRV group; 1586, MMR + V group; 529, MMR group). There were 663 confirmed v …
Characterization of Mycoplasma hyopneumoniae strains in vaccinated and non-vaccinated pigs from Spanish slaughterhouses.
Garza-Moreno L, Segalés J, Aragón V, Correa-Fiz F, Pieters M, Carmona M, Krejci R, Sibila M. Garza-Moreno L, et al. Vet Microbiol. 2019 Apr;231:18-23. doi: 10.1016/j.vetmic.2019.02.023. Epub 2019 Feb 20. Vet Microbiol. 2019. PMID: 30955807
Ten V and 10 NV fattening farms with respiratory problems associated to M. hyopneumoniae were selected. ...A total of 24 different TP(12 in V and 12 in NV farms) or 17 TP(9 in V and 9 in NV farms, being one TP in both farm types) were identified by ana …
Ten V and 10 NV fattening farms with respiratory problems associated to M. hyopneumoniae were selected. ...A total of 24 diffe …
Complementary Feeding Practices and Parental Pressure to Eat among Spanish Infants and Toddlers: A Cross-Sectional Study.
Klerks M, Roman S, Bernal MJ, Haro-Vicente JF, Sanchez-Siles LM. Klerks M, et al. Int J Environ Res Public Health. 2021 Feb 18;18(4):1982. doi: 10.3390/ijerph18041982. Int J Environ Res Public Health. 2021. PMID: 33670769 Free PMC article.
Solids, often cereals and/or fruits first, were introduced at a median age of five months. Fish and eggs were introduced around the age of nine and ten months. Almost all children were fed with home-prepared foods at least once per week (93%), and in 36% of the cases, salt …
Solids, often cereals and/or fruits first, were introduced at a median age of five months. Fish and eggs were introduced around the age of n …
[Classification of polydactyly of the hand and foot].
Buck-Gramcko D, Behrens P. Buck-Gramcko D, et al. Handchir Mikrochir Plast Chir. 1989 Jul;21(4):195-204. Handchir Mikrochir Plast Chir. 1989. PMID: 2767539 German.
In the transverse axis the affected rays are designated with Roman numbers from I to V. The longitudinal axis from distal to proximal is used to differentiate the rays into ten types according to their duplication assessed both anatomically and radiologically …
In the transverse axis the affected rays are designated with Roman numbers from I to V. The longitudinal axis from distal to p …
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice.
Mora AL, Torres-González E, Rojas M, Xu J, Ritzenthaler J, Speck SH, Roman J, Brigham K, Stecenko A. Mora AL, et al. Am J Respir Crit Care Med. 2007 Jun 1;175(11):1139-50. doi: 10.1164/rccm.200610-1426OC. Epub 2007 Mar 15. Am J Respir Crit Care Med. 2007. PMID: 17363768 Free PMC article.
Viral replication during the chronic phase of infection was controlled by two methods: the administration of cidofovir, an antiviral drug effective at clearing lytic but not latent virus, and by using a mutant gamma-herpesvirus defective in virus reactivation from latency. MEASUR …
Viral replication during the chronic phase of infection was controlled by two methods: the administration of cidofovir, an antiviral drug ef …
JO 1784, a potent and selective ligand for rat and mouse brain sigma-sites.
Roman FJ, Pascaud X, Martin B, Vauché D, Junien JL. Roman FJ, et al. J Pharm Pharmacol. 1990 Jun;42(6):439-40. doi: 10.1111/j.2042-7158.1990.tb06588.x. J Pharm Pharmacol. 1990. PMID: 1979628
JO 1784 ((+)-cinnamyl-1-phenyl-1-N-methyl-N-cyclopropylene) is a potent ligand for (+)-[3H]SKF 10,047 (2'-hydroxy-5,9-dimethyl-2-allyl-6,7-benzomorphan) binding sites in rat brain membrane preparations with an IC50 of 39 +/- 8 nM, which is comparable to that of haloperidol. The s …
JO 1784 ((+)-cinnamyl-1-phenyl-1-N-methyl-N-cyclopropylene) is a potent ligand for (+)-[3H]SKF 10,047 (2'-hydroxy-5,9-dimethyl-2-allyl-6,7-b …
[Serotypes and antibiotic susceptibility of Streptococcus pneumoniae in children in the health district of Valencia and Castellón, Spain: a multicenter, prospective trial].
Cantón E, Montaner M, Pérez-Bellés C, Román J, Moreno R, Igual R, González-Granda D, Gobernado M. Cantón E, et al. Rev Esp Quimioter. 2003 Dec;16(4):412-20. Rev Esp Quimioter. 2003. PMID: 14961135 Free article. Spanish.
A study was conducted to determine the serotypes, the coverage of the heptavalent conjugate vaccine (VCN 7-v) and the antibiotic susceptibility of Streptococcus pneumoniae in children (<15 years) in the health districts of the provinces of Castellon and Valencia, Spain, …
A study was conducted to determine the serotypes, the coverage of the heptavalent conjugate vaccine (VCN 7-v) and the antibiotic susc …
[Comparison between penicillin and amoxicillin-clavulanic acid for the treatment of recurrent tonsillopharyngitis in childhood].
Asensi F, López-Hontangas JL, Otero M, Santos M, Román J, Pérez-Tamarit D. Asensi F, et al. Rev Esp Quimioter. 1999 Sep;12(3):211-4. Rev Esp Quimioter. 1999. PMID: 10878510 Clinical Trial. Spanish.
Fifty-one children aged 2-14 years with recurrent tonsillopharyngitis, presenting dysphagia, fever and lymphadenitis, with more than two similar episodes in the last three years and showing a beta-hemolytic group A streptococci in the pharyngeal smear, were studied. They underwen …
Fifty-one children aged 2-14 years with recurrent tonsillopharyngitis, presenting dysphagia, fever and lymphadenitis, with more than two sim …