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Integrated care for older multimorbid heart failure patients: protocol for the ESCAPE randomized trial and cohort study.
Zelenak C, Nagel J, Bersch K, Derendorf L, Doyle F, Friede T, Herbeck Belnap B, Kohlmann S, Skou ST, Velasco CA, Albus C, Asendorf T, Bang CA, Beresnevaite M, Bruun NE, Burg MM, Buhl SF, Gaede PH, Lühmann D, Markser A, Nagy KV, Rafanelli C, Rasmussen S, Søndergaard J, Sørensen J, Stauder A, Stock S, Urbinati S, Riva DD, Wachter R, Walker F, Pedersen SS, Herrmann-Lingen C; ESCAPE consortium. Zelenak C, et al. ESC Heart Fail. 2023 Jun;10(3):2051-2065. doi: 10.1002/ehf2.14294. Epub 2023 Mar 12. ESC Heart Fail. 2023. PMID: 36907651 Free PMC article.
Heterologous expression of the atypical tetracycline chelocardin reveals the full set of genes required for its biosynthesis.
Lukežič T, Pikl Š, Zaburannyi N, Remškar M, Petković H, Müller R. Lukežič T, et al. Microb Cell Fact. 2020 Dec 19;19(1):230. doi: 10.1186/s12934-020-01495-x. Microb Cell Fact. 2020. PMID: 33341113 Free PMC article.
RESULTS: We report heterologous expression of the CHD biosynthetic gene cluster in the model organism Streptomyces albus del14 strain. Unexpectedly, we found that the originally defined CHD gene cluster fails to provide all genes required for CHD formation, including an ad …
RESULTS: We report heterologous expression of the CHD biosynthetic gene cluster in the model organism Streptomyces albus del14 strain …