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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 2
2004 5
2005 4
2006 6
2007 9
2008 5
2009 3
2010 5
2011 6
2012 6
2013 4
2014 13
2015 8
2016 12
2017 10
2018 4
2019 7
2020 5
2021 3
2022 1
2023 5
2024 4

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118 results

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Page 1
KMT9 Controls Stemness and Growth of Colorectal Cancer.
Berlin C, Cottard F, Willmann D, Urban S, Tirier SM, Marx L, Rippe K, Schmitt M, Petrocelli V, Greten FR, Fichtner-Feigl S, Kesselring R, Metzger E, Schüle R. Berlin C, et al. Among authors: schule r. Cancer Res. 2022 Jan 15;82(2):210-220. doi: 10.1158/0008-5472.CAN-21-1261. Epub 2021 Nov 4. Cancer Res. 2022. PMID: 34737213
Selective targeting of epigenetic reader domains.
Greschik H, Schüle R, Günther T. Greschik H, et al. Among authors: schule r. Expert Opin Drug Discov. 2017 May;12(5):449-463. doi: 10.1080/17460441.2017.1303474. Epub 2017 Mar 14. Expert Opin Drug Discov. 2017. PMID: 28277835 Review.
Histone demethylation and androgen-dependent transcription.
Metzger E, Wissmann M, Schüle R. Metzger E, et al. Among authors: schule r. Curr Opin Genet Dev. 2006 Oct;16(5):513-7. doi: 10.1016/j.gde.2006.08.013. Epub 2006 Aug 17. Curr Opin Genet Dev. 2006. PMID: 16919442 Review.
Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity.
Wang S, Klein SO, Urban S, Staudt M, Barthes NPF, Willmann D, Bacher J, Sum M, Bauer H, Peng L, Rennar GA, Gratzke C, Schüle KM, Zhang L, Einsle O, Greschik H, MacLeod C, Thomson CG, Jung M, Metzger E, Schüle R. Wang S, et al. Among authors: schule r. Nat Commun. 2024 Jan 2;15(1):43. doi: 10.1038/s41467-023-44243-6. Nat Commun. 2024. PMID: 38167811 Free PMC article.
Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas.
Lopez C, Schleussner N, Bernhart SH, Kleinheinz K, Sungalee S, Sczakiel HL, Kretzmer H, Toprak UH, Glaser S, Wagener R, Ammerpohl O, Bens S, Giefing M, Sanchez JCG, Apic G, Hubschmann D, Janz M, Kreuz M, Mottok A, Muller JM, Seufert J, Hoffmann S, Korbel JO, Russell RB, Schule R, Trumper L, Klapper W, Radlwimmer B, Lichter P, Kuppers R, Schlesner M, Mathas S, Siebert R. Lopez C, et al. Among authors: schule r. Haematologica. 2023 Feb 1;108(2):543-554. doi: 10.3324/haematol.2021.280005. Haematologica. 2023. PMID: 35522148 Free PMC article.
Lsd1 prevents age-programed loss of beige adipocytes.
Duteil D, Tosic M, Willmann D, Georgiadi A, Kanouni T, Schüle R. Duteil D, et al. Among authors: schule r. Proc Natl Acad Sci U S A. 2017 May 16;114(20):5265-5270. doi: 10.1073/pnas.1702641114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461471 Free PMC article.
KDM4 Inhibition Targets Breast Cancer Stem-like Cells.
Metzger E, Stepputtis SS, Strietz J, Preca BT, Urban S, Willmann D, Allen A, Zenk F, Iovino N, Bronsert P, Proske A, Follo M, Boerries M, Stickeler E, Xu J, Wallace MB, Stafford JA, Kanouni T, Maurer J, Schüle R. Metzger E, et al. Among authors: schule r. Cancer Res. 2017 Nov 1;77(21):5900-5912. doi: 10.1158/0008-5472.CAN-17-1754. Epub 2017 Sep 7. Cancer Res. 2017. PMID: 28883001
The complex genetics of epigenetics in urothelial carcinomas.
Frew IJ, Timmers HTM, Schüle R, Gratzke C. Frew IJ, et al. Among authors: schule r. Nat Rev Urol. 2020 Dec;17(12):655-656. doi: 10.1038/s41585-020-00386-5. Nat Rev Urol. 2020. PMID: 33037422 No abstract available.
118 results