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1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies.
Hagras M, Saleh MA, Ezz Eldin RR, Abuelkhir AA, Khidr EG, El-Husseiny AA, El-Mahdy HA, Elkaeed EB, Eissa IH. Hagras M, et al. Among authors: ezz eldin rr. J Enzyme Inhib Med Chem. 2022 Dec;37(1):380-396. doi: 10.1080/14756366.2021.2015342. J Enzyme Inhib Med Chem. 2022. PMID: 34923885 Free PMC article.
Pharmacophore-linked pyrazolo[3,4-d]pyrimidines as EGFR-TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies.
Gaber AA, El-Morsy AM, Sherbiny FF, Bayoumi AH, El-Gamal KM, El-Adl K, Al-Karmalawy AA, Ezz Eldin RR, Saleh MA, Abulkhair HS. Gaber AA, et al. Among authors: ezz eldin rr. Arch Pharm (Weinheim). 2021 Aug 31:e2100258. doi: 10.1002/ardp.202100258. Online ahead of print. Arch Pharm (Weinheim). 2021. PMID: 34467546
Ligand-based design and synthesis of N'-Benzylidene-3,4-dimethoxybenzohydrazide derivatives as potential antimicrobial agents; evaluation by in vitro, in vivo, and in silico approaches with SAR studies.
Ezz Eldin RR, Saleh MA, Alotaibi MH, Alsuair RK, Alzahrani YA, Alshehri FA, Mohamed AF, Hafez SM, Althoqapy AA, Khirala SK, Amin MM, A F Y, AbdElwahab AH, Alesawy MS, Elmaaty AA, Al-Karmalawy AA. Ezz Eldin RR, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1098-1119. doi: 10.1080/14756366.2022.2063282. J Enzyme Inhib Med Chem. 2022. PMID: 35430934 Free PMC article.