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Page 1
The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells.
Antioxidants (Basel). 2018 Dec 3;7(12):179. doi: 10.3390/antiox7120179.
Antioxidants (Basel). 2018.
PMID: 30513914
Free PMC article.
Review.
Inducible nitric oxide synthase inhibitor 1400W increases Na+ ,K+ -ATPase levels and activity and ameliorates mitochondrial dysfunction in Ctns null kidney proximal tubular epithelial cells.
Sumayao R Jr, Newsholme P, McMorrow T.
Sumayao R Jr, et al.
Clin Exp Pharmacol Physiol. 2018 Nov;45(11):1149-1160. doi: 10.1111/1440-1681.12998. Epub 2018 Jul 30.
Clin Exp Pharmacol Physiol. 2018.
PMID: 29924417
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Lysosomal cystine accumulation promotes mitochondrial depolarization and induction of redox-sensitive genes in human kidney proximal tubular cells.
Sumayao R, McEvoy B, Newsholme P, McMorrow T.
Sumayao R, et al.
J Physiol. 2016 Jun 15;594(12):3353-70. doi: 10.1113/JP271858. Epub 2016 Apr 10.
J Physiol. 2016.
PMID: 26915455
Free PMC article.
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Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels.
McEvoy B, Sumayao R, Slattery C, McMorrow T, Newsholme P.
McEvoy B, et al. Among authors: sumayao r.
J Physiol. 2015 Dec 1;593(23):5167-82. doi: 10.1113/JP271237. Epub 2015 Nov 18.
J Physiol. 2015.
PMID: 26482480
Free PMC article.
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Cystine dimethylester loading promotes oxidative stress and a reduction in ATP independent of lysosomal cystine accumulation in a human proximal tubular epithelial cell line.
Sumayao R, McEvoy B, Martin-Martin N, McMorrow T, Newsholme P.
Sumayao R, et al.
Exp Physiol. 2013 Oct;98(10):1505-17. doi: 10.1113/expphysiol.2013.073809. Epub 2013 Jun 28.
Exp Physiol. 2013.
PMID: 23813804
Free article.
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