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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1966 1
1975 3
1976 3
1978 1
1979 1
1981 1
1982 3
1983 1
1984 2
1985 1
1986 2
1987 5
1988 7
1989 5
1990 4
1991 4
1992 4
1993 16
1994 3
1995 4
1996 8
1997 4
1998 4
1999 14
2000 16
2001 9
2002 8
2003 14
2004 18
2005 21
2006 26
2007 23
2008 16
2009 30
2010 32
2011 30
2012 30
2013 29
2014 48
2015 46
2016 51
2017 63
2018 62
2019 57
2020 67
2021 70
2022 60
2023 75
2024 25

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901 results

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Page 1
A global view of hepatocellular carcinoma: trends, risk, prevention and management.
Yang JD, Hainaut P, Gores GJ, Amadou A, Plymoth A, Roberts LR. Yang JD, et al. Nat Rev Gastroenterol Hepatol. 2019 Oct;16(10):589-604. doi: 10.1038/s41575-019-0186-y. Epub 2019 Aug 22. Nat Rev Gastroenterol Hepatol. 2019. PMID: 31439937 Free PMC article. Review.
All these risk factors are potentially preventable, highlighting the considerable potential of risk prevention for decreasing the global burden of HCC. HCC surveillance and early detection increase the chance of potentially curative treatment; however, HCC surveillance is …
All these risk factors are potentially preventable, highlighting the considerable potential of risk prevention for decreasing the global bur …
Understanding interobserver agreement: the kappa statistic.
Viera AJ, Garrett JM. Viera AJ, et al. Fam Med. 2005 May;37(5):360-3. Fam Med. 2005. PMID: 15883903 Free article.
Studies that measure the agreement between two or more observers should include a statistic that takes into account the fact that observers will sometimes agree or disagree simply by chance. The kappa statistic (or kappa coefficient) is the most commonly used statistic for …
Studies that measure the agreement between two or more observers should include a statistic that takes into account the fact that observers …
Noonan Syndrome.
Roberts AE. Roberts AE. 2001 Nov 15 [updated 2022 Feb 17]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2001 Nov 15 [updated 2022 Feb 17]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301303 Free Books & Documents. Review.
Each child of an individual with autosomal dominant NS has a 50% chance of inheriting the pathogenic variant. NS caused by pathogenic variants in LZTR1 can be inherited in either an autosomal dominant or an autosomal recessive manner. ...If both parents are heterozygous fo …
Each child of an individual with autosomal dominant NS has a 50% chance of inheriting the pathogenic variant. NS caused by pathogenic …
Biotinidase Deficiency.
Wolf B. Wolf B. 2000 Mar 24 [updated 2023 May 25]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2000 Mar 24 [updated 2023 May 25]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301497 Free Books & Documents. Review.
If both parents are known to be heterozygous for a BTD pathogenic variant, each sib of an affected individual has at conception a 25% chance of being affected, a 50% chance of being an asymptomatic carrier, and a 25% chance of being unaffected and not a carri …
If both parents are known to be heterozygous for a BTD pathogenic variant, each sib of an affected individual has at conception a 25% cha …
Mutational heterogeneity in cancer and the search for new cancer-associated genes.
Lawrence MS, Stojanov P, Polak P, Kryukov GV, Cibulskis K, Sivachenko A, Carter SL, Stewart C, Mermel CH, Roberts SA, Kiezun A, Hammerman PS, McKenna A, Drier Y, Zou L, Ramos AH, Pugh TJ, Stransky N, Helman E, Kim J, Sougnez C, Ambrogio L, Nickerson E, Shefler E, Cortés ML, Auclair D, Saksena G, Voet D, Noble M, DiCara D, Lin P, Lichtenstein L, Heiman DI, Fennell T, Imielinski M, Hernandez B, Hodis E, Baca S, Dulak AM, Lohr J, Landau DA, Wu CJ, Melendez-Zajgla J, Hidalgo-Miranda A, Koren A, McCarroll SA, Mora J, Crompton B, Onofrio R, Parkin M, Winckler W, Ardlie K, Gabriel SB, Roberts CWM, Biegel JA, Stegmaier K, Bass AJ, Garraway LA, Meyerson M, Golub TR, Gordenin DA, Sunyaev S, Lander ES, Getz G. Lawrence MS, et al. Nature. 2013 Jul 11;499(7457):214-218. doi: 10.1038/nature12213. Epub 2013 Jun 16. Nature. 2013. PMID: 23770567 Free PMC article.
These studies involve the sequencing of matched tumour-normal samples followed by mathematical analysis to identify those genes in which mutations occur more frequently than expected by random chance. Here we describe a fundamental problem with cancer genome studies: as th …
These studies involve the sequencing of matched tumour-normal samples followed by mathematical analysis to identify those genes in which mut …
Vitrectomy.
Omari A, Mahmoud TH. Omari A, et al. 2023 Jul 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jul 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31869132 Free Books & Documents.
Pars plana vitrectomy (PPV) is a surgical technique originally introduced by Robert Machemer. The pars plana approach to the vitreous cavity allows access to the posterior segment to treat many vitreoretinal diseases. ...However, the procedure can also be associated with c …
Pars plana vitrectomy (PPV) is a surgical technique originally introduced by Robert Machemer. The pars plana approach to the vitreous …
The Nerve to Give BACE Inhibitors a Second Chance?
Baloh RH. Baloh RH. Neurotherapeutics. 2020 Jul;17(3):966-967. doi: 10.1007/s13311-020-00876-9. Neurotherapeutics. 2020. PMID: 32514890 Free PMC article. No abstract available.
Daratumumab, Cyclophosphamide, Bortezomib, Lenalidomide, and Dexamethasone as Induction and Extended Consolidation Improves Outcome in Ultra-High-Risk Multiple Myeloma.
Kaiser MF, Hall A, Walker K, Sherborne A, De Tute RM, Newnham N, Roberts S, Ingleson E, Bowles K, Garg M, Lokare A, Messiou C, Houlston RS, Jackson G, Cook G, Pratt G, Owen RG, Drayson MT, Brown SR, Jenner MW. Kaiser MF, et al. J Clin Oncol. 2023 Aug 10;41(23):3945-3955. doi: 10.1200/JCO.22.02567. Epub 2023 Jun 14. J Clin Oncol. 2023. PMID: 37315268
Comparison of PFS18m per Bayesian framework resulted in a 99.5% chance of OPTIMUM being superior to MyeXI. At 30 months' follow-up, PFS was 77% for OPTIMUM versus 39.8% for MyeXI, and OS 83.5% versus 73.5%, respectively. ...
Comparison of PFS18m per Bayesian framework resulted in a 99.5% chance of OPTIMUM being superior to MyeXI. At 30 months' follow-up, P …
WDR62 Primary Microcephaly.
Verloes A, Ruaud L, Drunat S, Passemard S. Verloes A, et al. 2022 Feb 17. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2022 Feb 17. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 35188728 Free Books & Documents. Review.
If both parents are known to be heterozygous for a WDR62 pathogenic variant, each sib of an affected individual has at conception a 25% chance of being affected, a 50% chance of being an asymptomatic carrier, and a 25% chance of being unaffected and not a car …
If both parents are known to be heterozygous for a WDR62 pathogenic variant, each sib of an affected individual has at conception a 25% c …
Exceptional Human Longevity.
Pignolo RJ. Pignolo RJ. Mayo Clin Proc. 2019 Jan;94(1):110-124. doi: 10.1016/j.mayocp.2018.10.005. Epub 2018 Dec 10. Mayo Clin Proc. 2019. PMID: 30545477 Review.
Overall, the aggregate literature supports that the basis for exceptional longevity is multifactorial and involves disparate combinations of genes, environment, resiliency, and chance, all of which are influenced by culture and geography....
Overall, the aggregate literature supports that the basis for exceptional longevity is multifactorial and involves disparate combinations of …
901 results