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Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity.
Hezaveh K, Shinde RS, Klötgen A, Halaby MJ, Lamorte S, Ciudad MT, Quevedo R, Neufeld L, Liu ZQ, Jin R, Grünwald BT, Foerster EG, Chaharlangi D, Guo M, Makhijani P, Zhang X, Pugh TJ, Pinto DM, Co IL, McGuigan AP, Jang GH, Khokha R, Ohashi PS, O'Kane GM, Gallinger S, Navarre WW, Maughan H, Philpott DJ, Brooks DG, McGaha TL. Hezaveh K, et al. Among authors: jin r. Immunity. 2022 Feb 8;55(2):324-340.e8. doi: 10.1016/j.immuni.2022.01.006. Immunity. 2022. PMID: 35139353 Free PMC article.
Dabrafenib alters MDSC differentiation and function by activation of GCN2.
Ciudad MT, Quevedo R, Lamorte S, Jin R, Nzirorera N, Koritzinsky M, McGaha TL. Ciudad MT, et al. Among authors: jin r. bioRxiv [Preprint]. 2023 Aug 16:2023.08.09.552588. doi: 10.1101/2023.08.09.552588. bioRxiv. 2023. PMID: 37645997 Free PMC article. Updated. Preprint.
Development of an In Vitro Test Method to Replace an Animal-Based Potency Test for Pertactin Antigen in Multivalent Vaccines.
Szeto J, Beharry A, Chen T, Zholumbetov E, Daigneault E, Ming M, Lounsbury I, Eng N, Thangavadivel N, Jin R, Denis-Jacquot A, Azad BB, Li M, Keizner D, Liu M, Lee SSF, He K, Gajewska B. Szeto J, et al. Among authors: jin r. Vaccines (Basel). 2023 Jan 27;11(2):275. doi: 10.3390/vaccines11020275. Vaccines (Basel). 2023. PMID: 36851153 Free PMC article.