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1948 1
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1960 1
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1964 1
1965 3
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1967 3
1968 4
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1971 6
1972 3
1973 5
1974 5
1975 3
1977 3
1978 1
1979 2
1980 3
1981 3
1982 3
1983 4
1984 2
1985 2
1986 3
1987 11
1988 10
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1990 16
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1995 15
1996 15
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1998 54
1999 80
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2004 113
2005 160
2006 176
2007 171
2008 147
2009 152
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The following term was not found in PubMed: Maioto
Page 1
Did you mean arita makoto (201 results)?
Rita Levi-Montalcini: the neurologist who challenged fascism.
Coutinho L, Teive HAG. Coutinho L, et al. Arq Neuropsiquiatr. 2023 Jan;81(1):95-98. doi: 10.1055/s-0043-1761426. Epub 2023 Mar 14. Arq Neuropsiquiatr. 2023. PMID: 36918012 Free PMC article. Review.
Rita Levi-Montalcini was a researcher in the field of neuroscience, Italian and Jewish in origin, who discovered the nerve growth factor and rightfully earned the 1986 Nobel Prize in Physiology or Medicine, alongside her collaborator Stanley Cohen. ...Despite these obstacl
Rita Levi-Montalcini was a researcher in the field of neuroscience, Italian and Jewish in origin, who discovered the nerve growth fac
Why Are We Scientists? Drawing Inspiration From Rita Levi-Montalcini.
Malerba F. Malerba F. Front Cell Neurosci. 2022 Jan 21;15:741984. doi: 10.3389/fncel.2021.741984. eCollection 2021. Front Cell Neurosci. 2022. PMID: 35126056 Free PMC article. Review.
In 2007, drawing inspiration from her previous experiments on chick embryos, Rita Levi-Montalcini, at the age of 98, proposed a new project, and a research group, in which I was included, was formed at the European Brain Research Institute (EBRI). ...This approach has alwa …
In 2007, drawing inspiration from her previous experiments on chick embryos, Rita Levi-Montalcini, at the age of 98, proposed a new p …
Rita Levi and Nerve Growth Factor.
Pai-Dhungat JV. Pai-Dhungat JV. J Assoc Physicians India. 2023 Sep;71(9):106. doi: 10.59556/japi.71.0343. J Assoc Physicians India. 2023. PMID: 38700311
How to cite this article: Pai-Dhungat JV. Rita Levi and Nerve Growth Factor. J Assoc Physicians India 2023;71(9):106-106....
How to cite this article: Pai-Dhungat JV. Rita Levi and Nerve Growth Factor. J Assoc Physicians India 2023;71(9):106-106....
Chk2 mediates RITA-induced apoptosis.
de Lange J, Verlaan-de Vries M, Teunisse AF, Jochemsen AG. de Lange J, et al. Cell Death Differ. 2012 Jun;19(6):980-9. doi: 10.1038/cdd.2011.182. Epub 2011 Dec 9. Cell Death Differ. 2012. PMID: 22158418 Free PMC article.
In addition, we observed an early p53- and Chk2-dependent block of DNA replication upon RITA treatment. Replicating cells seemed more prone to entering RITA-induced apoptosis. ...In conclusion, we identified Chk2 as an essential mediator of the cellular responses to …
In addition, we observed an early p53- and Chk2-dependent block of DNA replication upon RITA treatment. Replicating cells seemed more …
Decreased DNA Damage and Improved p53 Specificity of RITA Analogs.
Zhan Y, Zhou X, Peuget S, Singh M, Peyser BD, Fan Z, Selivanova G. Zhan Y, et al. Mol Cancer Ther. 2022 Oct 7;21(10):1524-1534. doi: 10.1158/1535-7163.MCT-22-0119. Mol Cancer Ther. 2022. PMID: 35877475 Free PMC article.
Several synthetic modifications to RITA's heterocyclic scaffold lead to higher energy barriers for carbocation formation. In this study, we addressed the question whether RITA analogs NSC777196 and NSC782846 can induce p53-dependent apoptosis without SULT1A1-depende …
Several synthetic modifications to RITA's heterocyclic scaffold lead to higher energy barriers for carbocation formation. In this stu …
Looking at the future with Rita.
Bentivoglio M. Bentivoglio M. Neuroscience. 2013 Nov 12;252:438-42. doi: 10.1016/j.neuroscience.2013.08.013. Neuroscience. 2013. PMID: 24288808
This paper on Rita Levi-Montalcini (1909-2012), who received in 1986 the Nobel Prize in Physiology or Medicine for the discovery of nerve growth factor, focuses on aspects of her advocacy and her commitment to education in which she has been especially active in the last p …
This paper on Rita Levi-Montalcini (1909-2012), who received in 1986 the Nobel Prize in Physiology or Medicine for the discovery of n …
RITA modulates cell migration and invasion by affecting focal adhesion dynamics.
Hoock SC, Ritter A, Steinhäuser K, Roth S, Behrends C, Oswald F, Solbach C, Louwen F, Kreis NN, Yuan J. Hoock SC, et al. Mol Oncol. 2019 Oct;13(10):2121-2141. doi: 10.1002/1878-0261.12551. Epub 2019 Aug 6. Mol Oncol. 2019. PMID: 31353815 Free PMC article.
Since RITA interacts with tubulin and coats microtubules of the cytoskeleton, we hypothesized that it is involved in cell motility. We show here that depletion of RITA reduces cell migration and invasion of diverse cancer cell lines and mouse embryonic fibroblasts. …
Since RITA interacts with tubulin and coats microtubules of the cytoskeleton, we hypothesized that it is involved in cell motility. W …
RITA Mimics: Synthesis and Mechanistic Evaluation of Asymmetric Linked Trithiazoles.
Pietkiewicz AL, Zhang Y, Rahimi MN, Stramandinoli M, Teusner M, McAlpine SR. Pietkiewicz AL, et al. ACS Med Chem Lett. 2017 Mar 6;8(4):401-406. doi: 10.1021/acsmedchemlett.6b00488. eCollection 2017 Apr 13. ACS Med Chem Lett. 2017. PMID: 28435526 Free PMC article.
The established cytotoxic agent RITA contains a thiophene-furan-thiophene backbone and two terminal alcohol groups. ...Evaluating the impact of 7h on proteins targeted by RITA (p53, c-Myc, and Mcl-1) indicated that it acts via a different mechanism of action to that …
The established cytotoxic agent RITA contains a thiophene-furan-thiophene backbone and two terminal alcohol groups. ...Evaluating the …
Targeting NF-kappaB RelA/p65 phosphorylation overcomes RITA resistance.
Bu Y, Cai G, Shen Y, Huang C, Zeng X, Cao Y, Cai C, Wang Y, Huang D, Liao DF, Cao D. Bu Y, et al. Cancer Lett. 2016 Dec 28;383(2):261-271. doi: 10.1016/j.canlet.2016.10.006. Epub 2016 Oct 6. Cancer Lett. 2016. PMID: 27721021
A phosphomimetic mutation at Ser536 (p65/S536D) or silencing of endogenous RelA/p65 resensitized the RITA-resistant cells to RITA while the phosphomimetic mutant at Ser276 (p65/S276D) led to RITA resistance of naive cells. ...In the naive cells, ABCC6 deliver …
A phosphomimetic mutation at Ser536 (p65/S536D) or silencing of endogenous RelA/p65 resensitized the RITA-resistant cells to RITA
RITA requires eIF2alpha-dependent modulation of mRNA translation for its anti-cancer activity.
Ristau J, van Hoef V, Peuget S, Zhu J, Guan BJ, Liang S, Hatzoglou M, Topisirovic I, Selivanova G, Larsson O. Ristau J, et al. Cell Death Dis. 2019 Nov 7;10(11):845. doi: 10.1038/s41419-019-2074-3. Cell Death Dis. 2019. PMID: 31699971 Free PMC article.
Yet, mechanisms underlying the anticancer activity of RITA are incompletely understood. Here we show that RITA suppresses mRNA translation independently of p53 by inducing eIF2alpha phosphorylation. ...Moreover, inhibition of eIF2alpha phosphorylation attenuates pro …
Yet, mechanisms underlying the anticancer activity of RITA are incompletely understood. Here we show that RITA suppresses mRNA …
8,853 results