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HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Wang S, Matassoli F, Zhang B, Liu T, Shen CH, Bylund T, Johnston T, Henry AR, Teng IT, Tripathi P, Becker JE, Changela A, Chaudhary R, Cheng C, Gaudinski M, Gorman J, Harris DR, Lee M, Morano NC, Novik L, O'Dell S, Olia AS, Parchment DK, Rawi R, Roberts-Torres J, Stephens T, Tsybovsky Y, Wang D, Van Wazer DJ, Zhou T, Doria-Rose NA, Koup RA, Shapiro L, Douek DC, McDermott AB, Kwong PD. Wang S, et al. Among authors: chaudhary r. Cell Rep. 2023 Jul 25;42(7):112755. doi: 10.1016/j.celrep.2023.112755. Epub 2023 Jul 11. Cell Rep. 2023. PMID: 37436899 Free PMC article. Clinical Trial.
5'-Cap sequestration is an essential determinant of HIV-1 genome packaging.
Ding P, Kharytonchyk S, Kuo N, Cannistraci E, Flores H, Chaudhary R, Sarkar M, Dong X, Telesnitsky A, Summers MF. Ding P, et al. Among authors: chaudhary r. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2112475118. doi: 10.1073/pnas.2112475118. Proc Natl Acad Sci U S A. 2021. PMID: 34493679 Free PMC article.
Extraordinary Titer and Broad Anti-SARS-CoV-2 Neutralization Induced by Stabilized RBD Nanoparticles from Strain BA.5.
Wang Z, Zhang B, Ou L, Qiu Q, Wang L, Bylund T, Kong WP, Shi W, Tsybovsky Y, Wu L, Zhou Q, Chaudhary R, Choe M, Dickey TH, El Anbari M, Olia AS, Rawi R, Teng IT, Wang D, Wang S, Tolia NH, Zhou T, Kwong PD. Wang Z, et al. Among authors: chaudhary r. Vaccines (Basel). 2023 Dec 28;12(1):37. doi: 10.3390/vaccines12010037. Vaccines (Basel). 2023. PMID: 38250850 Free PMC article.
Identification of the initial nucleocapsid recognition element in the HIV-1 RNA packaging signal.
Ding P, Kharytonchyk S, Waller A, Mbaekwe U, Basappa S, Kuo N, Frank HM, Quasney C, Kidane A, Swanson C, Van V, Sarkar M, Cannistraci E, Chaudhary R, Flores H, Telesnitsky A, Summers MF. Ding P, et al. Among authors: chaudhary r. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17737-17746. doi: 10.1073/pnas.2008519117. Epub 2020 Jul 9. Proc Natl Acad Sci U S A. 2020. PMID: 32647061 Free PMC article.
Ultrapotent Broadly Neutralizing Human-llama Bispecific Antibodies against HIV-1.
Xu J, Zhou T, McKee K, Zhang B, Liu C, Nazzari AF, Pegu A, Shen CH, Becker JE, Bender MF, Chan P, Changela A, Chaudhary R, Chen X, Einav T, Kwon YD, Lin BC, Louder MK, Merriam JS, Morano NC, O'Dell S, Olia AS, Rawi R, Roark RS, Stephens T, Teng IT, Tourtellott-Fogt E, Wang S, Yang ES, Shapiro L, Tsybovsky Y, Doria-Rose NA, Casellas R, Kwong PD. Xu J, et al. Among authors: chaudhary r. Adv Sci (Weinh). 2024 May 5:e2309268. doi: 10.1002/advs.202309268. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38704686