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Page 1
Bifunctional Ligands for Inhibition of Tight-Binding Protein-Protein Interactions.
Bioconjug Chem. 2016 Aug 17;27(8):1900-10. doi: 10.1021/acs.bioconjchem.6b00293. Epub 2016 Jul 20.
Bioconjug Chem. 2016.
PMID: 27389935
Biofocussed chemoprospecting: An efficient approach for drug discovery.
Thakkar BS, Albrigtsen M, Svendsen JS, Andersen JH, Engh RA.
Thakkar BS, et al. Among authors: engh ra.
Chem Biol Drug Des. 2017 Jul;90(1):128-140. doi: 10.1111/cbdd.12934. Epub 2017 Feb 7.
Chem Biol Drug Des. 2017.
PMID: 28139899
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Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome.
Stensen W, Rothweiler U, Engh RA, Stasko MR, Bederman I, Costa ACS, Fugelli A, Svendsen JSM.
Stensen W, et al. Among authors: engh ra.
Pharmaceuticals (Basel). 2021 Nov 17;14(11):1170. doi: 10.3390/ph14111170.
Pharmaceuticals (Basel). 2021.
PMID: 34832952
Free PMC article.
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Diversity of bisubstrate binding modes of adenosine analogue-oligoarginine conjugates in protein kinase a and implications for protein substrate interactions.
Pflug A, Rogozina J, Lavogina D, Enkvist E, Uri A, Engh RA, Bossemeyer D.
Pflug A, et al. Among authors: engh ra.
J Mol Biol. 2010 Oct 15;403(1):66-77. doi: 10.1016/j.jmb.2010.08.028. Epub 2010 Aug 21.
J Mol Biol. 2010.
PMID: 20732331
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Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules.
Rothweiler U, Stensen W, Brandsdal BO, Isaksson J, Leeson FA, Engh RA, Svendsen JS.
Rothweiler U, et al. Among authors: engh ra.
J Med Chem. 2016 Nov 10;59(21):9814-9824. doi: 10.1021/acs.jmedchem.6b01086. Epub 2016 Oct 21.
J Med Chem. 2016.
PMID: 27736065
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