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Page 1
Human skin equivalents: Impaired barrier function in relation to the lipid and protein properties of the stratum corneum.
Adv Drug Deliv Rev. 2021 Aug;175:113802. doi: 10.1016/j.addr.2021.05.012. Epub 2021 May 18.
Adv Drug Deliv Rev. 2021.
PMID: 34015420
Free article.
Review.
The effect of PPAR isoform (de)activation on the lipid composition in full-thickness skin models.
Helder RWJ, Rousel J, Boiten WA, Gooris GS, Nadaban A, El Ghalbzouri A, Bouwstra JA.
Helder RWJ, et al.
Exp Dermatol. 2023 Apr;32(4):469-478. doi: 10.1111/exd.14733. Epub 2023 Jan 2.
Exp Dermatol. 2023.
PMID: 36541108
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Improved organotypic skin model with reduced quantity of monounsaturated ceramides by inhibiting stearoyl-CoA desaturase-1.
Helder RWJ, Rousel J, Boiten WA, Gooris GS, Nadaban A, El Ghalbzouri A, Bouwstra JA.
Helder RWJ, et al.
Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Apr;1866(4):158885. doi: 10.1016/j.bbalip.2021.158885. Epub 2021 Jan 11.
Biochim Biophys Acta Mol Cell Biol Lipids. 2021.
PMID: 33444760
Free article.
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Multitargeted Approach for the Optimization of Morphogenesis and Barrier Formation in Human Skin Equivalents.
Mieremet A, Helder RWJ, Nadaban A, Boiten WA, Gooris GS, El Ghalbzouri A, Bouwstra JA.
Mieremet A, et al. Among authors: helder rwj.
Int J Mol Sci. 2021 May 28;22(11):5790. doi: 10.3390/ijms22115790.
Int J Mol Sci. 2021.
PMID: 34071405
Free PMC article.
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The effects of LXR agonist T0901317 and LXR antagonist GSK2033 on morphogenesis and lipid properties in full thickness skin models.
Helder RWJ, Boiten WA, van Dijk R, Gooris GS, El Ghalbzouri A, Bouwstra JA.
Helder RWJ, et al.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Feb;1865(2):158546. doi: 10.1016/j.bbalip.2019.158546. Epub 2019 Oct 31.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020.
PMID: 31678517
Free article.
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In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling.
van Smeden J, Dijkhoff IM, Helder RWJ, Al-Khakany H, Boer DEC, Schreuder A, Kallemeijn WW, Absalah S, Overkleeft HS, Aerts JMFG, Bouwstra JA.
van Smeden J, et al. Among authors: helder rwj.
J Lipid Res. 2017 Dec;58(12):2299-2309. doi: 10.1194/jlr.M079376. Epub 2017 Oct 12.
J Lipid Res. 2017.
PMID: 29025868
Free PMC article.
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Monounsaturated fatty acids reduce the barrier of stratum corneum lipid membranes by enhancing the formation of a hexagonal lateral packing.
Mojumdar EH, Helder RW, Gooris GS, Bouwstra JA.
Mojumdar EH, et al. Among authors: helder rw.
Langmuir. 2014 Jun 10;30(22):6534-43. doi: 10.1021/la500972w. Epub 2014 May 27.
Langmuir. 2014.
PMID: 24818519
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