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TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.
Hegde RN, Chiki A, Petricca L, Martufi P, Arbez N, Mouchiroud L, Auwerx J, Landles C, Bates GP, Singh-Bains MK, Dragunow M, Curtis MA, Faull RL, Ross CA, Caricasole A, Lashuel HA. Hegde RN, et al. Among authors: faull rl. EMBO J. 2020 Sep 1;39(17):e104671. doi: 10.15252/embj.2020104671. Epub 2020 Aug 5. EMBO J. 2020. PMID: 32757223 Free PMC article.
Making (anti-) sense out of huntingtin levels in Huntington disease.
Evers MM, Schut MH, Pepers BA, Atalar M, van Belzen MJ, Faull RL, Roos RA, van Roon-Mom WM. Evers MM, et al. Among authors: faull rl. Mol Neurodegener. 2015 Apr 28;10:21. doi: 10.1186/s13024-015-0018-7. Mol Neurodegener. 2015. PMID: 25928884 Free PMC article.